Ethanolic extraction and GC-MS analysis of antioxidant and anticancer bioactive compounds from and .

Bioactive components used to treat human ailments are abundant in medicinal plants. and have therapeutic properties due to the presence of many phytonutrients. Gas chromatography-mass spectrometry (GC-MS) was used to evaluate the properties of the antioxidant and anticancer bioactive components found in the ethanolic extracts of and leaves.

COVID-19 and medicinal plants: A critical perspective.

On a global scale, the Coronavirus pandemic (COVID-19) is having a direct and indirect effect on human lives, socioeconomic conditions, and the natural environment. The measures are taken to prevent the spread of coronavirus and slowdown of economic activities could have major short and long term effects on the natural ecosystem and climate in the coming days. Based on the current scientific studies, the present perspective intends to examine the possible direct and indirect impacts of the COVID-19 pandemic on the ecosystem particularly on medicinal plants.

Effect of Bacoside A on growth and biofilm formation by Staphylococcus aureus and Pseudomonas aeruginosa.

The goal of this study was to evaluate the antibiofilm and antimicrobial activities of Bacoside A, a formulation of phytochemicals from Bacopa monnieri, against Staphylococcus aureus and Pseudomonas aeruginosa, which are known to form biofilms as one of their virulence traits. The antimicrobial effects of Bacoside A were tested using the minimum inhibitory concentration and minimum bactericidal concentration assays. A cell membrane disruption assay was performed to find its possible target site.

Synthesis of Isomeric and Potent Impurities of the Triazole-Based Antifungal Drug Voriconazole.

We describe the synthesis of two positional isomers and a desfluoro impurity of Voriconazole starting with Friedel-Crafts acylation of mono- and difluorobenzene. These isomers are the crucial components in determining the quality of Voriconazole during its manufacturing from the key raw material, 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one. All the prepared impurities were characterized by IR, (1)H-NMR, (13)C-NMR, and mass spectral data.

An impression cytology based study of ocular surface in an urban population.

To assess the health of ocular surface in a defined urban population, conjunctival goblet cell density and degree of surface squamous metaplasia were utilized as study tools. Two thousand names of those aged between 20 and 79 years from the 2006 electoral register in ward number 63 of Kolkata Corporation area were initially selected. Normal healthy human volunteers without any history of ocular surface disorder were recruited and divided into five age-groups.

Lipoblastomatosis--a case report.

Lipoblastoma and lipoblastomatosis are benign fatty tumors of soft tissues that are unique to childhood. A male infant aged 5 months presented with a history of recurrent lump in the left scapular region. He had been operated upon for the same lump 2 months earlier.