Oral itraconazole for the treatment of severe seborrhoeic dermatitis.

Background: Seborrheic dermatitis (SD) is an inflammatory skin disorder in which colonies of Malassezia furfur have been found in affected areas.

Aim: The aim of this study was to evaluate the efficacy of itraconazole in the treatment of severe SD.

Materials And Methods: Itraconazole was given to 30 patients of SD in a dose of 100 mg twice daily for 1 week followed by 200 mg/day for first 2 days of the following 2 months.

Kindler'S syndrome: a case series of three Indian children.

Kindler's syndrome is a very rare genodermatosis characterized by acral blistering starting in infancy, photosensitivity, progressive poikiloderma, cutaneous atrophy, and various forms of mucosal involvement. A large number of other cutaneous and extracutaneous features have also been described. We report here three cases of Kindler's syndrome from eastern India for the rarity of the syndrome and to emphasize the importance of considering this condition in the differential diagnosis of disorders that can cause blistering, cutaneous atrophy, and/or poikilodermatous skin changes.

Bacteriological study of aerobic isolates from plantar ulcers of paucibacillary leprosy patients.

Background: Plantar ulcers commonly occur in leprosy patients, which usually recur and cause morbidity in such cases.

Aims: The aim of the study is to find out the bacteriological profile of these ulcers and to find out the antibiotic susceptibility of the isolates so that appropriate drugs may be chosen for treatment and for prevention of recurrence.

Materials And Methods: Fifty-six samples from recurrent plantar ulcers of paucibacillary leprosy patients (attending the outpatient department of Calcutta School of Tropical Medicine) were studied for the purpose.

No association between seropositivity for hepatitis C virus and lichen planus: a case control study.

Background: The epidemiological association of lichen planus (LP) with hepatitis C virus (HCV) infection has been recorded from some countries and HCV RNA3 has been isolated from lesional skin in patients with LP and chronic HCV infection. The observed geographical differences regarding HCV infection and LP could be immuno-genetically related.

Aim: To determine whether HCV has a causal relationship with LP.