Publications by authors named "Jayasree Peroth Jayaprakash"
Article Synopsis
- N6-methyladenosine (m6A) is a crucial regulator in RNA functions and is linked to cancer, particularly head and neck squamous cell carcinoma (HNSCC), which has a low survival rate.
- Research indicates that m6A RNA methylation is elevated in HNSCC and affects various cancer-related processes like growth, cell death, and metastasis.
- The study suggests that m6A modifications can serve as potential biomarkers for diagnosing and predicting outcomes in HNSCC and aims to provide a thorough review of m6A's role in cancer mechanisms.
Eukaryotes carry hundreds of ribosomal RNA (rRNA) genes as tandem arrays, which generate rRNA for protein synthesis. Humans carry ∼ 400 rRNA gene copies and their expression is epigenetically regulated. Dysregulation of rRNA synthesis and ribosome biogenesis are characteristic features of cancers.
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