Publications by authors named "Jayasimha Rayulu Daddam"
Plant systemic acquired resistance compound salicylic acid as a potent inhibitor against SCF (SKP1-CUL1-F-box protein) mediated complex in by homology modeling and molecular dynamics simulations.
Narendra Kumar Papathoti Chanon Saengchan Jayasimha Rayulu Daddam Nattaya Thongprom Kodchaphon Tonpho
J Biomol Struct Dyn
March 2022
Article Synopsis
- Many crop plants suffer economic losses due to root rot, necrosis, and wilting caused by certain pathogens.
- Molecular dynamics studies and homology modeling are being used to analyze the SKP1-CUL1-F-box protein complex to find effective ways to control it using salicylic acid.
- The research reveals that specific amino acids in the SCF complex strongly interact with salicylic acid, enhancing its binding and thereby providing potential for improved plant resistance against stress.