Publications by authors named "Jayashi Rajapakse"
Semin Liver Dis
November 2024
Article Synopsis
- - The global prevalence of Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is increasing, but effective treatments are still scarce.
- - Research is focusing on the connection between the gut microbiome and MASLD, with the potential for gut-targeted therapies to help manage or prevent the disease.
- - This review will explore how the gut microbiome's structure and function relate to MASLD, evaluate gut microbiome signatures for diagnosing disease severity, and look into both current and potential therapies targeting the interactions between the gut microbiome and liver.
Gut Microbes
December 2023
Article Synopsis
- * Specific bacteria and gut-related metabolites have been shown to play significant roles in HCC development, leading to interest in dietary changes, probiotics, and fecal microbiota transplantation as potential treatments.
- * Early research suggests that modifying the gut microbiota may improve liver function, reduce inflammation, and hinder tumor growth, indicating a promising direction for liver cancer therapy.
