Publications by authors named "Jayaraman J"

Background: Exposure to hairs of caterpillars and moths are collectively termed as lepidopterism. Clinical manifestations include cutaneous presentation of localized stinging reaction with wheals or vesiculation, acute urticarial papules and plaques, ophthalmic, oropharyngeal involvement to severe life-threatening anaphylactic reactions with angioedema.

Aims: In this study we have determined the prevalence of various cutaneous, oropharyngeal and ophthalmic manifestations of lepidopterism at a tertiary health care center.

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Vitiligo is a depigmenting disorder characterized by melanocyte loss, which results in pigment dilution of the skin. Vitiligo is commonly associated with thyroid disorders and thyroid stimulating hormone (TSH) is a sensitive marker to detect thyroid disorders. S100B is damage associated molecular pattern (DAMP) molecule released when there is melanocyte damage.

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Objectives: Breast cancer is the most common cancer in the UK, accounting for 15% of all new cases in women. Evidence still points to disparities in outcomes linked to ethnicity and screening uptake is overall lower in South Asians than the White population. We investigated the experiences and perceptions of Gujarati Hindu community members on their 'cancer journeys'.

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Extensive pesticide use in Trinidad and Tobago (T&T) raises concerns for human and environmental health. Therefore, this study sought to assess the general knowledge, attitudes and practices of T&T residents on pesticides and related topics. Using convenience (non-probability) sampling, a questionnaire was administered to residents of Trinidad ( = 572) and Tobago ( = 68).

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  • Reducing contaminants in wastewater is crucial for improving water quality in both industrialized and developing nations, leading to a focus on algae-based microbial reactors for treatment.
  • Algae-based membrane bioreactors (MBRs) merge the benefits of traditional MBRs with algae, but prior studies have overlooked the details of their performance and the specific types of wastewater being treated.
  • The study aims to evaluate the effectiveness of algae in treating wastewater, compare it to other techniques, and analyze the technical challenges faced when implementing algae-based systems for removing emerging contaminants.
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Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) has decimated kiwifruit orchards growing susceptible kiwifruit Actinidia chinensis varieties. Effector loss has occurred recently in Psa3 isolates from resistant kiwifruit germplasm, resulting in strains capable of partially overcoming resistance present in kiwiberry vines (Actinidia arguta, Actinidia polygama, and Actinidia melanandra).

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  • Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious skin reactions mainly triggered by drugs, and SCORTEN is used to predict their severity and mortality risk.
  • A recent study sought to determine if the neutrophil-lymphocyte ratio (NLR) could serve as a prognostic marker for SJS/TEN by analyzing patient data over four years from a hospital.
  • Although a weak positive correlation was found between NLR and SCORTEN, it wasn’t statistically significant, suggesting that while NLR indicates systemic inflammation, its effectiveness in predicting disease severity needs further research with more patients.
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Objectives: The overall pooled success rate of the Hall Technique (HT) in various types of studies has not been investigated. The present study aims to evaluate the success rate of HT to restore carious primary molars.

Methods: A systematic search was carried out in the MEDLINE/PubMed, Excerpta Medica Database (EMBASE), Scopus, Web of Science, and LIVIVO electronic databases, as well as the ProQuest database for grey literature review.

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  • Dermatophytosis is a prevalent skin infection that has become more complex due to drug resistance, highlighting the need for standardized assessment tools like the Dermatophytosis Severity Score (DSS).
  • A pilot study involving 25 adults revealed consistent evaluations of disease severity over 8 weeks, showing a high recurrence rate and the impact of prior steroid use among patients.
  • The DSS proved to be a reliable tool correlating well with patient-reported outcomes on itch and quality of life, emphasizing its importance in managing dermatophytosis effectively.
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Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) causes a devastating canker disease in yellow-fleshed kiwifruit (Actinidia chinensis). The effector HopZ5, which is present in all isolates of Psa3 causing global outbreaks of pandemic kiwifruit canker disease, triggers immunity in Nicotiana benthamiana and is not recognised in susceptible A.

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Background: Motivational interviewing (MI) is an approach to increase parental compliance to follow up and recall of their children. It has proven to be successful in motivating parents to adopt and maintain preventive child oral health behaviors.

Aim: To assess the effectiveness of motivational interviewing on prevention strategies for parents of children who have received full-mouth dental rehabilitation under general anesthesia (GA).

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Objectives: Antibiotic-resistant Klebsiella pneumoniae is a human pathogen of major global concern due to its ability to cause multiple severe diseases that are often difficult to treat therapeutically. This study aimed to investigate the resistome of local clinical K. pneumoniae isolates.

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  • Copper resistance in phytopathogens poses a significant global threat to crop production, largely due to the extensive use of copper-based pesticides.
  • Recent studies indicate that exposure to heavy metals may lead to the co-selection of resistance genes for both heavy metals and antibiotics in bacteria, affecting disease dynamics across plants, animals, and humans.
  • In this study, strains of Xanthomonas campestris and Xanthomonas melonis from infected crucifer plants in Trinidad showed resistance to multiple heavy metals and antibiotics, highlighting the genetic similarities between these strains and other bacteria, as well as their resistance mechanisms.
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Background: Dermatophytosis has assumed epidemic proportions with rising resistance, recalcitrance and recurrence, especially in tropical regions. While various factors contribute to high prevalence worldwide, yet little is known about the interactions between host defence mechanisms and dermatophytes, particularly in chronic and recalcitrant dermatophytosis.

Objectives: We aimed to compare the population of various immune cells in specimens of chronic recurrent dermatophytosis and those with acute superficial dermatophytosis.

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  • The study examines how the bacterium Xanthomonas campestris pv. campestris (Xcc) responds to copper stress, using RNA sequencing to analyze gene expression after exposure to copper sulfate for 15 minutes.
  • Initial findings show changes in genes involved in stress response, biofilm formation, and metal efflux, with particular focus on the copper homeostasis gene (cohL) and a chromosomal efflux operon (czcCBA).
  • Results suggest that Xcc utilizes a combination of mechanisms to combat oxidative stress and enhance heavy metal resistance, indicating the presence of efflux genes possibly adapted for broader metal detoxification.
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is a primary sylvan vector of yellow fever virus and the emerging Mayaro virus. However, despite its medical importance, there is a dearth of data on the molecular taxonomy of this mosquito species. In this study, DNA barcoding analysis was performed on 64 adult female mosquitoes from Trinidad morphologically identified as The mitochondrial (COI) gene and ribosomal DNA internal transcribed spacer 2 (ITS2) region of the mosquitoes were PCR amplified and sequenced, and molecular phylogenies inferred.

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Itraconazole (ITZ) has been the mainstay of oral antifungal treatment for the current epidemic of recalcitrant dermatophytosis (RD) in India. Recently, a newer formulation of ITZ, super bioavailable itraconazole (SUBA-ITZ), is made available in the market by many pharmaceutical companies. It is important for dermatologists to understand the pharmacokinetic properties of SUBA-ITZ vis-a-vis conventional pellet formulation to use it effectively and safely.

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Arabidopsis thaliana WRKY proteins are potential targets of pathogen-secreted effectors. RESISTANT TO RALSTONIA SOLANACEARUM 1 (RRS1; AtWRKY52) is a well-studied Arabidopsis nucleotide-binding and leucine-rich repeat (NLR) immune receptor carrying a C-terminal WRKY domain that functions as an integrated decoy. RRS1-R recognizes the effectors AvrRps4 from Pseudomonas syringae pv.

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Aim: To evaluate the average age and primary reason for the first dental visit among patients with special health care needs (SHCN) as well as to examine barriers related to accessing care for children with special health care needs.

Methods: This is a cross-sectional survey that was distributed to caregivers of children with special health care needs (CSHCN).  Study data was collected through REDCap, a secure web-based survey application.

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To present evidence-based recommendations on nonpharmacological behavior guidance for the pediatric dental patient. The work group assessed eight systematic reviews for effectiveness of nonpharmacological behavior guidance techniques in children undergoing preventive care or a dental treatment visit. The key outcomes assessed included cooperative behavior, anxiety, and procedural pain.

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Context: Many therapeutic modalities have been reported for the treatment of warts: a common bothersome condition; however, no single treatment is completely effective.

Aims: This study aimed to evaluate the efficacy and safety of intralesional injection of measles, mumps and rubella (MMR) vaccine and to compare its efficacy with 85% formic acid puncture for common warts.

Settings And Design: This was a prospective comparative study.

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A patient with status epilepticus presents with a grossly carious primary molar. Medical consultation is requested from the patient's neurologist. The patient is treated in the operating room under general anesthesia for comprehensive dental care.

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The purpose of this study was to assess the knowledge, attitude, and training of pediatric dental residents and faculty on the management of patients who belong to the LGBTQ (lesbian, gay, bisexual, transgender, and queer) community. This cross-sectional survey included a 16-item questionnaire to assess the attitudes and training regarding the LGBTQ population, separately for pediatric dental residents and faculty across the United States. Statistical significance was set at the level of five percent, and data were analyzed using descriptive statistics, Wilcoxon rank-sum, and Fisher's exact tests.

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Objectives:  The purpose of this study is to systematically appraise the reporting quality of abstracts for randomized controlled trials (RCT) published in pediatric dentistry using Consolidated Standards of Reporting Trials (CONSORT) for abstracts and to analyze the relationship between the characteristics of the RCT to the quality of abstracts.

Materials And Methods:  RCTs published in Pediatric Dentistry were retrieved from the PubMed database from 2016 to 2021. The quality of abstracts was appraised using CONSORT for abstracts checklist by two independent reviewers.

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