Publications by authors named "Jayanti Bhattacharya"
J Biomol Struct Dyn
October 2020
Article Synopsis
- The study focuses on two food-derived peptides, RALP and WYT, which have antihypertensive effects by inhibiting both renin and angiotensin-converting enzyme (ACE) in the Renin-Angiotensin System.
- Molecular docking and dynamics simulations were employed to analyze how these peptides interact with renin and ACE, revealing different binding behaviors that influence their effectiveness.
- Findings suggest that while the peptides are less effective at binding to renin due to potential displacement from critical areas, they remain stable in ACE's binding site, indicating opportunities for improving their dual-targeting capabilities.
