Publications by authors named "Jayanta Samanta"
1: ESGE recommends the combination of endoscopic ultrasound-guided tissue acquisition (EUS-TA) and endoscopic retrograde cholangiopancreatography (ERCP)-based tissue acquisition as the preferred diagnostic approach for tissue acquisition in patients with jaundice and distal extrahepatic biliary stricture in the absence of a pancreatic mass. 2: ESGE suggests that brushing cytology should be completed along with fluoroscopy-guided biopsies, wherever technically feasible, in patients with perihilar biliary strictures. 3: ESGE suggests EUS-TA for perihilar strictures when ERCP-based modalities yield insufficient results, provided that curative resection is not feasible and/or when cross-sectional imaging has shown accessible extraluminal disease.
View Article and Find Full Text PDFPolycyclic aromatic hydrocarbons (PAHs) are carcinogenic and persistent organic pollutants in water. Their removal is highly challenging for existing generic and nonspecific adsorbents, creating an urgent need for tailored solutions. Herein, a metal-"organic cage" framework, MOF-CC-1, designed for the effective scavenging of PAHs from water is is introduced.
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- * Researchers isolated and characterized two triterpene isomers that co-crystallized in a consistent 67:33 ratio, confirming their structure using various advanced techniques.
- * Four additional compounds were successfully isolated, with lutein and dyscusin C identified for the first time from this particular plant.*
Article Synopsis
- Acute pancreatitis (AP) is a serious condition that can range from mild to severe, with complications like infections and organ failure becoming more common due to the increased presence of multi-drug-resistant organisms linked to improper antibiotic use.
- * The study aims to explore the experiences of patients with suspected infected pancreatic necrosis (IPN), focusing on identifying the prevalence of multi-drug-resistant organisms (MDROs) and understanding their antibiotic resistance.
- * Data was collected from 130 patients at a tertiary hospital in India, revealing that a majority had significant pancreatic necrosis, with high rates of organ failure and infections, particularly in the respiratory tract, and showing specific microbial resistance patterns.
The increasing threat of antibiotic resistance has created an urgent need for new antibacterial agents, particularly plant-based natural compounds and their derivatives. Thymol, a natural monoterpenoid phenolic compound derived from , is known for its aromatic and therapeutic properties, including antibacterial activity. This study focuses on synthesizing dihydropyrimidinone and dihydropyridine derivatives of thymol and exploring their antibacterial properties.
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- - ERCP (endoscopic retrograde cholangiopancreatography) is a crucial procedure for diagnosing and treating biliopancreatic disorders, utilizing a mix of endoscopy and radiology to address issues like bile duct stones and leaks.
- - The procedure often requires anesthesia due to its discomfort, with options ranging from moderate sedation to general anesthesia, making the choice of anesthetic methods significant.
- - A narrative review was conducted to evaluate current anesthetic medications used during elective ERCP, particularly focusing on new drugs like dexmedetomidine, amidst ongoing debates about sedation levels and airway management practices.
Article Synopsis
- The text refers to a correction made to a previously published article.
- The specific article mentioned can be identified by its DOI, which is 10.1055/a-2411-1814.
- Corrections like this are common in academic publishing to address errors or inaccuracies in research.
Article Synopsis
- - The study investigated outcomes of lumen-apposing metal stents (LAMS) placement in patients with surgically altered anatomy (SAA), which is not well-documented in existing literature, involving 270 patients across 25 tertiary care centers up to November 2023.
- - Technical success of the procedures was very high at 98%, with clinical success at 97%, although there was a notable adverse event rate of 12%, with various degrees of severity recorded.
- - The results suggest that while LAMS placement in SAA is effective, due to the risk of complications, these procedures should only be performed by experienced endoscopists in specialized centers.
Encapsulated pancreatic fluid collection (PFC) is a requisite for endoscopic drainage procedures. The 4-week threshold for defining walled-off necrosis does not capture the dynamic process of encapsulation. We aim to investigate the changes in the wall characteristics of PFC in acute necrotizing pancreatitis (ANP) by comparing baseline contrast-enhanced computed tomography (CECT) with follow-up CT scans.
View Article and Find Full Text PDFBackground And Objectives: Endoscopic ultrasound-guided biliary drainage (EUS-BD) is a viable alternative in cases with failed ERCP transpapillary drainage (ERCP-TPD). This systematic review and meta-analysis aimed to compare the efficacy and safety of EUS-BD and ERCP-TPD for primary biliary drainage in patients with distal malignant biliary obstruction (DMBO).
Methods: We searched Embase, PubMed, and Medline databases for studies comparing EUS-BD and ERCP-TPD in DMBO, from inception until September 2023.
Same versus separate sessions of endoscopic ultrasound-guided fine-needle biopsy and endoscopic retrograde cholangiopancreatography for distal malignant biliary obstruction: a propensity score-matched study.
Expert Rev Gastroenterol Hepatol
September 2024
Background: Same-session endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) is an attractive policy for patients with distal malignant biliary obstruction (DMBO) requiring fine-needle biopsy (FNB) and biliary drainage. However, scanty and conflicting data exists regarding safety and efficacy when comparing these two procedures performed in same versus separate sessions.
Methods: Single-center, retrospective, propensity score-matched study including patients with DMBO who underwent EUS-FNB followed by ERCP during the same or separate sessions.
Article Synopsis
- - Endoscopic ultrasound (EUS) was first used for vascular interventions in 2000, focusing initially on sclerotherapy for esophageal varices, and now commonly aids in gastric variceal therapy and portosystemic pressure gradient (PPG) measurements.
- - Additional emerging EUS interventions include ectopic variceal obliteration, splenic artery embolization, and portal venous sampling, showcasing its expanding applications in treating vascular conditions.
- - Following the 2023 commentary from the American Gastroenterological Association endorsing EUS for specific therapies, recent studies continue to support its growing role in various vascular interventions, which is analyzed in this review.
Background: The standard salvage technique used for difficult bile duct cannulation is precut sphincterotomy, whereas endoscopic ultrasound-guided rendezvous technique (EUS-RV) is a relatively newer method. Prospective comparative data between these 2 techniques as salvage for biliary access in patients with benign biliary disease and difficult bile duct cannulation is lacking.
Objective: To compare EUS-RV and precut sphincterotomy as salvage technique for difficult bile duct cannulation in benign biliary obstruction.
Background And Aims: Limited evidence exists regarding the impact of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on upper endoscopy. Therefore, a meta-analysis was conducted to comprehensively review the available evidence on this subject.
Methods: A systematic bibliographic search was carried out until May 2024.
Background: Since there is no current international consensus on the optimal approach for pain management in acute pancreatitis (AP), analgesic practices may vary across different healthcare settings.
Objective: This study explored global disparities in analgesic use, in particular opioids, during admission and at discharge in hospitalised AP patients.
Methods: This was a post hoc analysis of the prospective PAINAP database, which included all admissions for AP between April and June 2022 with a 1-month follow-up.
Pancreatic cystic lesions (PCLs) pose a diagnostic challenge due to their increasing incidence and the limitations of cross-sectional imaging and endoscopic-ultrasound-guided fine-needle aspiration (EUS-FNA). EUS-guided through the needle biopsy (EUS-TTNB) has emerged as a promising tool for improving the accuracy of cyst type determination and neoplastic risk stratification. EUS-TTNB demonstrates superior diagnostic performance over EUS-FNA, providing critical preoperative information that can significantly influence patient management and reduce unnecessary surgeries.
View Article and Find Full Text PDFEndoscopic ultrasound-guided pancreatic duct drainage: a comprehensive state of the art review.
Expert Rev Gastroenterol Hepatol
July 2024
Introduction: Endoscopic retrograde pancreatography (ERP) has traditionally been the standard modality for pancreatic endotherapy. However, in certain situations, failure of retrograde ductal access may warrant an alternative modality of drainage. This can occur in various settings like difficult and/or surgically altered anatomy or duodenal obstruction.
View Article and Find Full Text PDFBackground: Longitudinal incision is the commonly used incision for entry into the submucosal space during peroral endoscopic myotomy (POEM) for esophageal motility disorders. Transverse incision is another alternative for entry and retrospective data suggest it has less operative time and chance of gas-related events.
Methods: This was a single-center, randomized trial conducted at a tertiary care hospital.
Article Synopsis
- The study compares the effectiveness of endoscopic ultrasound-guided liver biopsy (EUS-LB) and percutaneous liver biopsy (PC-LB) based on data from randomized controlled trials (RCTs).
- Both biopsy methods showed similar sample adequacy and diagnostic accuracy, but PC-LB resulted in longer, non-fragmented tissue specimens.
- Ultimately, while EUS-LB and PC-LB are comparable in diagnosis, PC-LB offers an advantage in specimen length according to the findings.
Article Synopsis
- The study investigates how the timing of percutaneous catheter drainage (PCD) after endoscopic cystogastrostomy (CG) influences clinical outcomes in patients with acute pancreatitis and walled-off necrosis (WON).
- Researchers divided patients into groups based on the interval between endoscopic CG and PCD, assessing outcomes like hospital stay length, ICU time, need for surgery, and mortality.
- Results showed no significant differences in clinical outcomes across different timing groups, indicating that the timing of PCD does not impact patient recovery.
Background: Endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) is an alternative for biliary drainage in patients with obstructive pancreaticobiliary pathology when endoscopic retrograde cholangiopancreatography (ERCP) is not feasible. Despite its effectiveness, EUS-HGS is associated with a significant risk of adverse events. This study aimed to evaluate the feasibility and safety of a newly designed dedicated cautery-enhanced tubular self-expandable metal stent (SEMS) for EUS-HGS.
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- Endoscopic submucosal dissection (ESD) is an advanced technique for removing early tumors, initially used for gastric lesions, now expanding to more complex areas like the colorectum.
- The review discusses the growing variety of devices available for colorectal ESD, focusing on their indications and which tools are best suited for specific situations.
- While some devices may offer distinct advantages, the choice often depends on personal preference and experience, making it crucial for endoscopists to understand the tools and their functions to provide optimal patient care.