A systematic review and meta-analysis on the efficacy of intravesical therapy for bladder pain syndrome/interstitial cystitis.

Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic disease characterised by persistent irritating micturition symptoms and pain. The objective was to compare the clinical efficacy of currently available products for intravesical therapy of BPS/IC and to assess their pharmacoeconomic impact. A Pubmed/Medline database search was performed for articles on intravesical therapy for BPS/IC.

Paediatric balanitis xerotica obliterans: an 8-year experience.

Objective: Balanitis Xerotica Obliterans (BXO) is rarely described in the paediatric population. We report our 8-year experience, at Harold Wood Hospital, with BXO in circumcised boys.

Materials And Methods: Pathological tissue diagnoses of BXO from 1997 to 2005 were extracted from our histopathology database.

Urinary tract dysfunction in Parkinson's disease: a review.

Introduction: Parkinson's disease is an extrapyramidal neurological disorder. Although motor symptoms are a predominant feature of the condition, non-motor symptoms have also been recognized. Urinary symptoms are frequently present in patients affected with Parkinson's disease (PD).

Hydroxyurea therapy: a rare cause of reversible azoospermia.

Background: Essential thrombocythaemia (ET) is an uncommon chronic myeloproliferative disorder characterized by a marked increase in the number of platelets. Hydroxyurea is effective in preventing thrombosis in high-risk patients with essential thrombocythaemia. In previous studies different side effects of Hydroxyurea have been pointed out, but attention has not really been focused on the possible side effects on spermatogenesis.