A self-assembled clavanin A-coated amniotic membrane scaffold for the prevention of biofilm formation by ocular surface fungal pathogens.

Amniotic membrane (AM) is frequently used in ophthalmologic surgery for rapid ocular surface reconstruction. Sometimes it may create a major problem with associated infections after biofilm formation over the membrane. To overcome this problem, AM was coated with the antimicrobial peptide clavanin A.

Kaajal fights against eye pathogens and is safe for eye make-up: a reinvestigation of an ancient practice.

The present report includes a scientific view of the traditional use of 'Kaajal' from the leaf of Euphorbia neriifolia, an Indian spurge tree locally called the 'Monosha' plant. A thorough analysis of the material demonstrates that it contains carbon nanoparticles having two uniform sizes of 2-3 nm and 35-45 nm. Further study revealed that Kaajal has antimicrobial properties against eye pathogens and is biocompatible for cosmetic use.

Comparison of Goldmann Tonometry and Dynamic Contour Tonometry in Normal and Descemet Stripping Endothelial Keratoplasty Eyes.

Purpose: This study aimed to compare intraocular pressures (IOP) measured by dynamic contour tonometry (DCT) with Goldmann tonometry (GAT) in Descemet stripping endothelial keratoplasty (DSEK) eyes. The agreeability between the 2 established methods and their relation to central corneal thickness (CCT) was also studied.

Design: A comparative case series.

Rhodotorula mucilaginosa Keratitis: a rare fungus from Eastern India.

Rhodotorula mucilaginosa rarely cause keratitis in immunocompromised individuals. A 30 year old male with history of minor trauma presented with cotton wool like stromal infiltration and hypopyon in left eye. Microbiological examination of corneal scraping showed fungal hyphae and yeast cells in direct smear.

N, N'-Olefin functionalized bis-imidazolium gold(I) salt is an efficient candidate to control keratitis-associated eye infection.

Keratitis treatment has become more complicated due to the emergence of bacterial or fungal pathogens with enhanced antibiotic resistance. The pharmaceutical applications of N-heterocyclic carbene complexes have received remarkable attention due to their antimicrobial properties. In this paper, the new precursor, 3,3'-(p-phenylenedimethylene) bis{1-(2- methyl-allyl)imidazolium} bromide (1a) and its analogous PF6 salt (1b) were synthesized.

Schizophyllum commune: a new organism in eye infection.

Purpose: We report a case of mycotic keratitis caused by a rare fungus Schizophyllum commune.

Methods: Clinical examination, slit-lamp examination, and microbiological evaluation of the corneal ulcer were done, and its treatment outcome was studied. The fungal etiology was established by conventional microbiological techniques, polymerase chain reaction and speciation by DNA sequencing.

Candida fermentati: a rare yeast involved in fungal keratitis.

Purpose: The aim of this study was to report a rare case of fungal keratitis from Eastern India.

Methods: This is a case report.

Results: A 52-year-old man with a history of minor trauma presented with a total corneal ulcer and hypopyon in the left eye.

Lasiodiplodia theobromae keratitis: a case report and review of literature.

A case report and review of literature is reported of a rare case of fungal keratitis from eastern India. A 32-year-old woman with a history of vegetative trauma presented with keratitis in left eye. Microbiological examination of corneal scraping showed refractile hyphae with aseptate branching filaments and black pigmented colonies on multiple solid agar medium.

Effects of lactoferricin B against keratitis-associated fungal biofilms.

Biofilms are considered as the most important developmental characteristics in ocular infections. Biofilm eradication is a major challenge today to overcome the incidence of drug resistance. This report demonstrates the in vitro ability of biofilm formation on contact lens by three common keratitis-associated fungal pathogens, namely, Aspergillus fumigatus, Fusarium solani, and Candida albicans.

Candida keratitis: emerging problem in India.

Purpose: To determine the epidemiological characteristics and outcome of Candida keratitis in a Cornea Care Unit of Kolkata-based tertiary eye hospital.

Methods: A retrospective, noncomparative, observational case series involving patients of culture-proven fungal keratitis from January 2008 to December 2008. A total of 85 cases of culture-proven fungal keratitis were identified.

Characteristics of microsporidial keratoconjunctivitis in an eastern Indian cohort: a case series.

Background: Microsporidia are intracellular parasites responsible for human infections. Recently, there has been an increase in the incidence of microsporidial keratoconjunctivitis (MKC) affecting normal individuals worldwide.

Aim: To determine the characteristics of MKC in an Indian cohort.

Epidemiological profile of fungal keratitis in urban population of West Bengal, India.

Background: Corneal diseases are one of the major causes of visual loss and blindness, second only to cataract. Amongst corneal diseases, microbial keratitis is a major blinding disease. In some countries, fungal keratitis accounts for almost 50% of patients with culture-proven microbial keratitis.

Bacterial keratitis after manual descemet stripping endothelial keratoplasty--a different pathophysiology?

Purpose: To report two cases of infective keratitis caused by Pseudomonas aeruginosa after manual descemet stripping endothelial keratoplasty (DSEK).

Method: Case report.

Results: Case 1, a 65-year-old woman, presented with a central corneal infiltrate after manual DSEK for pseudophakic bullous keratopathy, 6 weeks before this presentation.