Immunohistochemical differentiation of inflammatory myopathies.

Background: Idiopathic inflammatory myopathies are a heterogeneous group of acquired muscle disorders with considerable overlap in the histological features, making histological diagnosis difficult at times.

Aims: To determine the immunohistochemical profile of clinically suspected cases of inflammatory myopathies, using monoclonal antibodies to HLA-1 and membrane attack complex (MAC), and to correlate the clinical, serological, and electromyographic profile and the histopathological picture, with the immunohistochemical profile.

Settings And Design: This was a retrospective study analyzing the clinical and histopathological features in muscle of clinically suspected cases of inflammatory myopathy and correlating it to their HLA-1 and MAC immunostaining profiles.

Multicentric small cell neuroendocrine neoplasm of the renal pelvis and ureter with concomitant focal high-grade urothelial carcinoma of the ureter: A case report.

Malignant small cell neuroendocrine tumors of the pelvi-calyceal system are rare, and even more uncommon is their occurrence with concomitant transitional cell carcinoma, in the same renal unit. We present such a case for its unique presentation.

Use of single-photon emission computed tomography/low-resolution computed tomography fusion imaging in detecting an unusually presenting osteoid osteoma of the lumbar vertebra.

In this article, we describe an unusual presentation of osteoid osteoma of the lumbar vertebra in a woman in her early 30s. Single-photon emission computed tomography/low-resolution computed tomography (SPECT/CT) fusion imaging was used to detect the osteoma, precisely localize the pathology site, and guide surgical excision of the lesion. In recent years, SPECT/CT fusion imaging has helped make interpretations of scintigraphic images significantly more accurate.