Publications by authors named "Jayakumar N Doraiswamy"

Article Synopsis
  • - Guided bone regeneration is a technique that uses a barrier membrane over a bone graft site to prevent soft tissue growth, allowing slow-growing bone cells to establish properly for effective bone regeneration.
  • - The combination of chitosan and gelatin creates a scaffold that enhances bone healing, with chitosan providing structure and antimicrobial benefits, and gelatin promoting cell attachment and proliferation.
  • - A systematic review of six studies found that chitosan and gelatin scaffolds significantly improved bone repair, suggesting they could be vital in treating tissue loss from conditions like periodontitis, and future research should look into other biopolymer integrations for advancement.
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Aim Guided tissue regeneration (GTR) membranes have been used to encourage the regrowth of periodontal tissues, but traditional GTR membranes may not degrade at the right rate, which can lead to complications. Multifunctional scaffolds such as chitosan and gelatin-based scaffolds are designed to have controlled biodegradation, ensuring that they remain in place long enough to support tissue regeneration. These scaffolds are included with hemostatic properties that can help control bleeding, making the procedure safer for patients.

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Herbal medicines have long been used as a traditional mode of therapy for various ailments in India. They are being used increasingly as dietary supplements to ward off common diseases. Periodontal diseases are highly prevalent and can affect up to 90% of the world population.

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Ankyloglossia or tongue-tie is a congenital anomaly affecting the tongue, which is characterized by thick, short lingual frenulum. This condition causes many difficulties such as limited tongue protrusion, breastfeeding difficulties, speech impairment and lack of self-confidence. It is very rarely associated with any other congenital craniofacial disorders such as cleft lip, X-linked cleft palate, Van der Woude syndrome, Smith-Lemli-Opitz syndrome, Orofacial digital syndrome, Beckwith Weidman syndrome or Simpson-Golabi-Behmel syndrome.

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Background: Conventional anti-microbial therapy largely consisted of systemic administration of various drugs effective against periodontal pathogens, but fraught with several problems. Based on the concept of local drug delivery a bioresorbable device made of pure fibrillar collagen has been developed. The aim of this study was to study the release of Tetracycline from this collagen fiber (Type I collagen) impregnated with Tetracycline and its antibacterial activity against Porphyromonas gingivalis.

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