Repeated exacerbation of asthma: An intrinsic phenotype of uncontrolled asthma.

Asthma is a chronic disease of the airways affecting a large number of people across the globe. Uncontrolled asthma poses an emotional as well as the physical burden on patients and results in a great economic burden. "Exacerbation-prone phenotype" asthmatics are a cluster of patients who may suffer from more frequent and severe exacerbations than other asthmatics.