Publications by authors named "JayaLakshmi Thangaraj"
Front Immunol
January 2023
Article Synopsis
- The study investigates the combined effects of natural killer (NK) cells, bevacizumab (Bev), and irinotecan (Iri) on glioblastoma multiforme (GBM) in order to tackle the diverse nature of tumor cells.
- Researchers found that while Iri promotes both GBM cell proliferation and NK ligand expression, Bev does not significantly alter these processes but can enhance Iri's effect.
- The results show that injecting NK cells, especially directly into the tumor, improves the cytotoxic response against Bev and Iri-treated GBM cells, resulting in reduced tumor growth in a mouse model.
