Pharmacogenomic analysis of a genetically distinct Indigenous population.

Indigenous Australians face a disproportionately severe burden of chronic disease relative to other Australians, with elevated rates of morbidity and mortality. While genomics technologies are slowly gaining momentum in personalised treatments for many, a lack of pharmacogenomic research in Indigenous peoples could delay adoption. Appropriately implementing pharmacogenomics in clinical care necessitates an understanding of the frequencies of pharmacologically relevant genetic variants within Indigenous populations.

Correction: Role of defective states in MgO nanoparticles on the photophysical properties and photostability of MEH-PPV/MgO nanocomposite.

Correction for 'Role of defective states in MgO nanoparticles on the photophysical properties and photostability of MEH-PPV/MgO nanocomposite' by Sangeetha Ashok Kumar , , 2021, , 22804-22816, DOI: 10.1039/d1cp03035c.

Role of defective states in MgO nanoparticles on the photophysical properties and photostability of MEH-PPV/MgO nanocomposite.

Hybrid organic-inorganic nanocomposites employ metal oxides to improve the charge transport properties and stability of the conjugated polymer. They are considered one of the most interesting candidates for optoelectronic applications. This article presents a detailed investigation on the influence of defective electronic states of MgO nanoparticles on the photophysical properties and photostability of a conjugated polymer, poly[2-methoxy-5-(2-ethylhyxyloxy)-1,4-phenylene vinylene] (MEH-PPV).

5-Aminosalicylic acid attenuates allergen-induced airway inflammation and oxidative stress in asthma.

Pro-inflammatory cytokines regulate the magnitude of allergic reactions during asthma. Tumor necrosis factor--alpha (TNF-α), interleukin-6 (IL-6) and interleukin-13 (IL-13) play a crucial role in aggravating the inflammatory conditions during allergic asthma. In addition, oxidative stress contributes to the pathogenesis of asthma by altering the physiological condition resulting in the development of status asthmaticus.

High-speed WDM-PON using CW injection-locked Fabry-Pérot laser diodes.

We propose a new WDM-PON architecture using Fabry-Pérot laser diodes (FP-LDs) that are injection-locked by continuous wave (CW) seed light. The modulation characteristics of the CW light injection-locked FP-LD are first investigated. Both uplink and downlink transmissions at 10 Gb/s are experimentally demonstrated using the proposed CW injection-locked FP-LDs.