Monozygotic twins with early-onset schizophrenia and late-onset bipolar disorder: a case report.

Introduction: Schizophrenia and bipolar disorder are generally considered to be distinct illnesses. One piece of evidence supporting their distinctness is the rarity of schizophrenia and bipolar disorder occurring in monozygotic co‒twins.

Case Presentation: We describe a well-characterized pair of African American, female, monozygotic twins assessed at 53 years of age.

The art and rationale of applying a compression dressing.

Compression dressings are commonly used by medical and nursing staff to arrest bleeding in a trauma or first aid situation. Their use on surgical wounds may reduce blood loss, wound ooze and infection risk. We have seen variation in the techniques used by staff in our Orthopaedic department, often resulting in no compression being achieved.

Breakpoint Associated with a novel 2.3 Mb deletion in the VCFS region of 22q11 and the role of Alu (SINE) in recurring microdeletions.

Background: Chromosome 22q11.2 region is highly susceptible to rearrangement, specifically deletions that give rise to a variety of genomic disorders including velocardiofacial or DiGeorge syndrome. Individuals with this 22q11 microdeletion syndrome are at a greatly increased risk to develop schizophrenia.

Poor glycemic control is associated with increased diastolic blood pressure and heart rate in children with Type 1 diabetes.

Although higher levels of hemoglobin A1c (HbA1c) and blood pressure precede the development of nephropathy in Type 1 diabetes (T1DM), the relationship between glycemic control and cardiovascular factors early in the course of diabetes is not clear. We conducted a retrospective study from clinic data for a 1-year period in 148 children with T1DM aged 12.5+/-4.