Homology Modeling of Enolase and its Molecular Interaction with Novel Inhibitors.

Introduction: The treatment of Indian tropical disease such as kala-azar is likely to be troublesome to the clinicians as AmpB- and miltefosine-resistant has been reported. The rationale behind designed a novel inhibitors of model of enolase and performing a binding study with its inhibitors to gain details of the interaction between protein residues and ligand molecules.

Methods And Materials: The enolase model consists of two typical domains.