Publications by authors named "Jay K Wathen"
We characterized the natural history of metastatic renal cell carcinoma (RCC) and identified prognostic factors among patients who did or did not undergo allogeneic hematopoietic stem cell transplantation (HSCT). A total of 99 patients (23 who underwent HSCT and 76 who did not) were included in the study. Overall survival rates were comparable between the HSCT and no-HSCT groups (excluding patients with poor performance status or brain metastasis from the latter group) at a median 17.
View Article and Find Full Text PDFBackground: Colitis is a rare but serious gastrointestinal complication associated with taxane-based chemotherapy in patients with cancer. The incidence, clinical presentation, and outcome of colitis in patients with breast carcinoma treated with taxane-based chemotherapy is not known.
Methods: The authors searched their electronic database and identified patients with breast carcinoma who were treated with taxane-based chemotherapy between January 1997 and December 1999.
Adaptive randomized study of idarubicin and cytarabine versus troxacitabine and cytarabine versus troxacitabine and idarubicin in untreated patients 50 years or older with adverse karyotype acute myeloid leukemia.
J Clin Oncol
May 2003
Article Synopsis
- Troxacitabine was evaluated for treating untreated adverse karyotype acute myeloid leukemia (AML) in older patients, compared to traditional treatments with idarubicin and cytarabine.
- A randomized study was designed where patients were assigned to receive different combinations of chemotherapy, but adaptations favored more successful treatments over time.
- The results showed that the traditional IA regimen had a significantly higher complete remission rate than the troxacitabine combinations (TA and TI), indicating that troxacitabine was not superior in this context.