Exploring the therapeutic potential of Saudi (L.) DC. Essential oil: Insights into antioxidant, analgesic, and hepatorenal protective effects.

Lately, the herb's essential oils have received the intense attention of researchers and pharmaceutical agencies. The chemical composition, antioxidant, analgesic activity, anti-hyperpyrexia, and hepatorenal protective effects of the (L.) DC.

Isochlorogenic Acid Glucosides from the Arabian Medicinal Plant and Their Antimicrobial Activities.

A phytochemical investigation of the stems of the Arabian plant afforded three new isochlorogenic acid derivatives, namely isochlorogenic acid A-3'---glucopyranoside (), isochlorogenic acid A-3'---glucopyranoside methyl ester (), and isochlorogenic acid C-3'---glucopyranoside (), obtained along with thirteen known secondary metabolites belonging to distinct structural classes. The structures of the new metabolites were elucidated by modern spectroscopic techniues based on high-resolution mass spectrometry (HR-ESIMS) and 1D/2D nuclear magnetic resonance (NMR). All isolated compounds were tested for their potential antimicrobial activity against four different bacterial strains (, , , and ), in addition to a fungal strain (), The results were expressed as the diameter of the clear zone (in millimetres) around each well.

Chemical Composition of Flowers Essential Oil and Hepato-Therapeutic Effect against Carbon Tetrachloride-Induced Toxicity (In-Vivo).

The liver is a crucial organ among body organs due to its wide functions, in particular, detoxification and metabolism. Exposure to detrimental chemicals or viral infections may provoke liver dysfunction and ultimately induce liver tissue damage. Finding natural substances for liver disease treatment to overcome the conventional treatments' side effects has attracted the attention of researchers worldwide.

Phytochemical Profiling, In Vitro Biological Activities, and In-Silico Studies of : An Unexplored Plant.

Forssk. (Moraceae family) is an important medicinal plant that has not been previously investigated for its phytochemical and biological potential. Phytochemical screening, total bioactive content, and GCMS analysis were used to determine its phytoconstituents profile.

Euphocactoside, a New Megastigmane Glycoside from Growing in Saudi Arabia.

A phytochemical investigation of the aerial parts of Ehrenb. ex Boiss. revealed a new megastigmane, euphocactoside (), along with eleven known metabolites.

Phytochemical Profiling, In Vitro Biological Activities, and In Silico Molecular Docking Studies of .

, a traditionally significant medicinal plant, has not been extensively explored before for its phytochemical and biological potential. The present study was conducted to evaluate the bioactive phytochemicals and in vitro biological activities of , and perform in silico molecular docking validation of . The bioactive phytochemicals were assessed by preliminary phytochemical testing, total bioactive contents, and GC-MS analysis.

A hepatonephro-protective phenolic-rich extract from red onion (Allium cepa L.) peels.

Onion peel is a common bio-waste, occasionally used in traditional medicine in treatment of liver ailment and inflammation. However, a phytochemical and biological study is further required to provide the scientific evidence for this use. A phenolic-rich extract of red onion peels (coded as ACPE) was primarily prepared and then subjected to chromatographic separation.

Hepatorenal protective effect of Antistax(®) against chemically-induced toxicity.

Background: Antioxidant natural products and chemoprevention are considered nowadays as an effective approach against health various disorders and diseases induced by oxidative stress or free radicals.

Objective: The aim of this study was to assess the hepato- and nephroprotective activity of a standardized red vine leaf aqueous extract AS195 (Antistax(®)).

Methods: The protective activity of AS195 (100 mg/kg) was investigated on carbon tetrachloride (CCl4)-intoxicated rats in comparison with silymarin.

Proanthocyanidin-rich date seed extract protects against chemically induced hepatorenal toxicity.

A hydroacetone extract was prepared from seeds of Phoenix dactylifera L. var. Khalas, which is an industrial by-product of date processing.