Chemical and antiviral study on alkaloids from Papaver pseudocanescens M. Pop.

The phytochemical investigation of the aerial parts of Papaver pseudocanescens M. Pop. of Mongolian origin resulted in the isolation and structural elucidation of 8 alkaloids of the isoquinoline and promorphinane type.

Protopine reduces the inflammatory activity of lipopolysaccharide-stimulated murine macrophages.

Protopine is an isoquinoline alkaloid contained in plants in northeast Asia. In this study, we investigated whether protopine derived from Hypecoum erectum L could suppress lipopolysaccharide (LPS)-induced inflammatory responses in murine macrophages (Raw 264.7 cells).

Alkaloids from Mongolian species Hypecoum lactiflorum Kar. et Kir. Pazij.

A new secoberbine alkaloid (-)-N-methylcorydalisol was isolated from the aerial parts of Hypecoum lactiflorum Kar. et Kir. Pazij.

Alkaloids from Papaver nudicaule L.

A new promorphinane alkaloid (-)-8,14-dihydroflavinantine was isolated from the aerial parts of Papaver nudicaule L. (Papaveraceae) growing in Mongolia. Six known isoquinoline alkaloids (+)-amuronine, pseudoprotopine, allocryptopine, (-)-dihydroamuronine, (-)-amurensinine N-oxide A and (-)-amurensinine N-oxide B were isolated, too.

A new 8,14-dihydropromorphinane alkaloid from Papaver nudicaule L.

A racem. 8,14-dihydroamurine is a new promorphinane alkaloid isolated from the aerial parts of Papaver nudicaule L. (Papaveraceae) of Mongolian origin.