Publications by Javor Pomakov

Publications by authors named "Javor Pomakov"

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Changes in cytokine profile during local IL-2 therapy in cancer patients.

Radosveta Tomova Javor Pomakov John J L Jacobs Dimcho Adjarov Svetlana Popova

Anticancer Res

August 2006

Background: Exogenous interleukin 2 (IL-2) can influence the complex cytokine network in vivo. This study investigated the cytokine profile of patients with different malignancies before and after local IL-2 administration.

Patients And Methods: The human TH1 / TH2 cytometric bead array (CBA) kit was used to investigate IL-2, IFNgamma, TNFalpha, IL-4, IL-5 and IL-10 in a control group and in 13 patients.

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- Javor Pomakov's research primarily focuses on the impact of interleukin 2 (IL-2) therapy on the cytokine profiles of cancer patients, examining how exogenous IL-2 influences the immune response in various malignancies.
- A notable study published in 2006 utilized a human TH1/TH2 cytometric bead array to analyze specific cytokines (IL-2, IFNgamma, TNFalpha, IL-4, IL-5, and IL-10) in both a control group and 13 cancer patients undergoing local IL-2 treatment.
- The findings suggest significant changes in the cytokine profiles post-IL-2 administration, indicating potential implications for optimizing immunotherapy strategies in oncology.

Publications by authors named "Javor Pomakov"

Changes in cytokine profile during local IL-2 therapy in cancer patients.

Synopsis of recent research by authors named "Javor Pomakov"