Manufacture and mechanical properties of knee implants using SWCNTs/UHMWPE composites.

This article focuses on obtaining ultra high molecular weight polyethylene (UHMWPE) material reinforced with functionalized single-walled carbon nanotubes (f-SWCNTs) and the manufacturing of unicompartmental knee implants via Single-Point Incremental Forming process (SPIF). The physicochemical properties of the developed UHMWPE reinforced with 0.01 and 0.

Engineering and evaluation of forcespun functionalized carbon nano-onions reinforced poly (ε-caprolactone) composite nanofibers for pH-responsive drug release.

Nanofibers and smart polymers are potentially fascinating biomaterials for the sustained release of therapeutic agents and tissue engineering applications. The current study describes a new class of pH-controlled polycaprolactone/mercaptophenyl methacrylate functionalized carbon nano-onions (PCL/f-CNOs) composite nanofibers by Forcespinning® (FS) with a sustained drug release profile. The morphology and structural characteristics of PCL/f-CNOs nanofibers were scrutinized by Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR), respectively.

Synergistic Combinations of Curcumin, Sulforaphane, and Dihydrocaffeic Acid against Human Colon Cancer Cells.

Nutraceutical combinations that act synergistically could be a powerful solution against colon cancer, which is the second deadliest malignancy worldwide. In this study, curcumin (C), sulforaphane (S), and dihydrocaffeic acid (D, a chlorogenic acid metabolite) were evaluated, individually and in different combinations, over the viability of HT-29 and Caco-2 colon cancer cells, and compared against healthy fetal human colon (FHC) cells. The cytotoxic concentrations to kill 50%, 75%, and 90% of the cells (CC, CC, and CC) were obtained, using the MTS assay.

Rational design and engineering of carbon nano-onions reinforced natural protein nanocomposite hydrogels for biomedical applications.

In the current study, poly 4-hydroxyphenyl methacrylate-carbon nano-onions (PHPMA-CNOs = f-CNOs) are synthesized and reinforced with natural protein gelatin (GL) to engineer GL/f-CNOs composite hydrogels under the sonochemical method. The influence of f-CNOs content on the mechanical properties of hydrogels is examined. Cytotoxicity of hydrogels is measured with the human osteoblast cells.

Advances in the Processing of UHMWPE-TiO to Manufacture Medical Prostheses via SPIF.

This research focuses on developing a novel ultra high molecular weight polyethylene (UHMWPE) material reinforced with titanium dioxide (TiO 2 ) nanoparticles for producing craniofacial prostheses via an incremental sheet forming process (SPIF). First, UHMWPE-TiO 2 nanocomposite sheets were produced using incipient wetting and the compression molding process by considering different concentrations of TiO 2 nanoparticles. Then, the influence that the compression molding fabrication process has on the crystallinity and structural properties of the produced sample sheets was investigated.

Cytotoxicity evaluation of unfunctionalized multiwall carbon nanotubes-ultrahigh molecular weight polyethylene nanocomposites.

The carbon nanotubes were chosen for this study since long, small to medium diameter, and unfunctionalized nanotubes are considered less favorable for nontoxic applications. The intent of the study is to expand the use of CNTs beyond current understood nontoxic means. Multiwall carbon nanotube/ultrahigh molecular weight polyethylene (MWCNT/UHMWPE) nanocomposites were prepared by reinforcing long chain UHMWPE with MWCNTs.

Microencapsulation of Corn Wastewater (Nejayote) Phytochemicals by Spray Drying and Their Release Under Simulated Gastrointestinal Digestion.

Corn lime cooking generates a large amount of wastewater known as nejayote that is composed of suspended solids and solubilized phytochemicals. Spray drying can be an alternative to recover bioactive molecules, such as ferulic acid, from nejayote. Besides the yield, the physicochemical properties (solubility, water activity, pH, moisture, hygroscopicity, total phenolic content, and distribution of free and bound hydroxycinnamic acids) of spray-dried nejayote powders were analyzed.