Rhabdomyolysis secondary to quetiapine.

Quetiapine is one of the drugs used most in current Psychiatry due to its therapeutic efficiency and clinical safety. We report the case of a 26-year-old male patient with severe mental retardation due to Y-chromosome partial deletion who initiated treatment with quetiapine for the control of his aggressiveness, and who developed severe rhabdomyolysis two weeks later. In spite of the confirmed clinical safety of quetiapine, doctors must monitor the appearance of rare but serious adverse effects as that presented in this clinical case.

[Legionella in a patient with rheumatoid arthritis receiving abatacept].

Abatacept is a new drug available for refractory Rheumatoid Arthritis (RA), as other biologic therapies this drug is not free of potentially serious adverse events. We present a case of a 73 year-old patient treated with abatacept who suffered a Legionella pneumophila type 1 pneumoniae.

[Rapid resolution of nitrofurantoin-induced interstitial lung disease].

We report the case of a 40-year-old woman diagnosed with interstitial lung disease due to long-term nitrofurantoin therapy. Despite severely distorted bronchiolar architecture and honeycombing confirmed by computed tomography of the thorax, transbronchial biopsy showed a pattern of acute/subacute interstitial pneumonitis and the symptoms and radiographic findings disappeared within 1 month after administration of prednisone. This case shows that nitrofurantoin-induced lung disease may run a benign course and respond favorably to corticosteroids, even when there is radiographic evidence of established lung fibrosis.