Publications by authors named "Javier Salmeron Escobar"

Eosinophilic cholecystitis (EC) is a rare disease that is characterised by eosinophilic infiltration of the gallbladder. Its pathogenesis is unknown, although many hypotheses have been made. Clinical and laboratory manifestations do not differ from those of other causes of cholecystitis.

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Objectives: The objectives of the present study were to determine the importance of amoxicillin-clavulanic acid (AC) hepatotoxicity in the paediatric population and to characterise the episodes identified and potential host-specific factors. This was addressed via a prospective observational study in which 8 Spanish hospitals participated.

Methods: A total of 11 cases were examined.

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Article Synopsis
  • Recurrent pyogenic cholangitis (RPC) is a condition mainly affecting Asian patients, characterized by the formation of pigment stones in the bile ducts, leading to repeated episodes of cholangitis and other complications.
  • It is important to differentiate RPC from other conditions that cause intrahepatic stone formation, as they are more common in Asia while gallstones are more prevalent in Western countries.
  • Effective diagnosis and treatment of RPC require teamwork among gastroenterologists, radiologists, and gastrointestinal surgeons, and its occurrence is becoming more frequent outside of Asia.
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For several years, liver biopsy has been the established gold standard for evaluating the status of liver disease in patients with chronic hepatitis C. Although this procedure continues to be recommended, current practice is changing for 2 main reasons: firstly, treatment is more effective and, secondly, biochemical and serological tests provide a great deal of information on disease progression. Pathologists can increase the importance and utility of liver biopsy in chronic hepatitis C, providing information not only on the stage of fibrosis and necroinflammatory activity but also on the grade of steatosis and iron accumulation, which are implicated in disease progression.

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