Publications by authors named "Javier Montoro"
Purpose: The objective of this study was to develop and validate a questionnaire, through a Delphi consensus, to be used by allergists in their routine clinical practice to assess the preferences of patients starting allergen immunotherapy (AIT) treatment using an objective approach.
Patients And Methods: A Delphi consensus-driven process was used. The scientific committee, composed of 15 allergists, led the study and participated in the preparation of the questionnaire.
Article Synopsis
- PM-allergoids are new vaccines designed to target dendritic cells and induce Treg cells, with this study focusing on their safety and optimal dosage for treating house dust mite allergies in humans.
- In a clinical trial with 196 participants, doses of PM-HDM were compared against placebos using various administration routes (subcutaneous and sublingual) over four months, measuring key outcomes like nasal provocation tests and symptom scores.
- Results showed that PM-HDM was safe, with significant improvements in allergy symptoms observed at higher doses, particularly at 3000 mTU for sublingual administration and 5000 mTU for subcutaneous administration.
Allergic rhinitis causes loss of smell in children: The OLFAPEDRIAL study.
Pediatr Allergy Immunol
December 2016
Background: The objective of the OLFAPEDRIAL study was to assess the olfactory dysfunction in allergic paediatric population, which has been scarcely studied.
Methods: Observational, cross-sectional and multicentre study evaluated the sense of smell in untreated allergic rhinitis (AR) paediatric patients aged 6-12 years.
Results: Forty-four per cent (551 of 1260) of children with AR reported smell dysfunction, with both loss of smell frequency (52.
Background: Allergic rhinitis (AR) is the most common chronic disease in children. The main objective of this study was to analyze the comorbidities and therapeutic approaches for AR in a Spanish pediatric population.
Methods: Children aged 6 to 12 years with AR were included in an observational, cross-sectional, multicenter study.
Introduction: Urticaria is a highly prevalent disease among people. First-choice treatment continues to be centred on the second-generation H1 antihistamines, including a wide group of drugs with a better therapeutic index (or risk:benefit ratio) than the classic ones, even in the high, off-label dosage occasionally required in chronic urticaria. Bilastine is a newly registered H1-antihistamine for treatment of allergic rhinoconjunctivitis and urticaria.
View Article and Find Full Text PDFBackground: Nasal polyposis (NP) is a chronic inflammatory disease of unknown etiology that impairs quality of life (QoL). The role of atopy in NP is not established. The aim of this study was to describe the clinical characteristics and QoL in a broad sample of patients with NP and to evaluate the influence of allergy on this disease.
View Article and Find Full Text PDFSEAIC-SEORL. Consensus Document on Nasal Polyposis. POLINA Project.
J Investig Allergol Clin Immunol
July 2011
Background: Although the prevalence of allergic rhinitis (AR) is increasing, relatively little is known about patient characteristics in Spain. The aim of this study was to investigate the clinical profile and therapeutic strategies in patients attending Spanish specialists for AR caused by grass pollen or house-dust mites (HDMs).
Methods: This was a multicenter cross-sectional epidemiological study of consecutive patients aged ≥5 years with confirmed diagnosis of AR caused by grass pollen or HDMs attending allergy specialists throughout Spain.
Allergic rhinitis (AR) is the commonest chronic disease in children. Allergic Rhinitis and its Impact on Asthma (ARIA) classification based on symptom duration (intermittent vs. persistent) and severity (mild vs.
View Article and Find Full Text PDFIntroduction: Allergic rhinitis (AR) is an increasingly prevalent worldwide disease, which has an important impact on quality of life and generates high social and health care costs. The ARIA classification, that considers both the duration and severity of AR, seems more appropriate than previous classifications of AR, but few studies exist on the validation of the severity criteria proposed by the ARIA classification.
Objectives: To assess the ARIA duration and severity classification of AR in a large sample population of patients, by investigating whether different degrees of severity correlate with differences in symptom score, quality of life or the patient's self evaluation of impairment.