Circumscribed Hypokeratosis: Report on a Series of 7 Mexican Cases and Review of the Literature.

Circumscribed palmoplantar hypokeratosis is a recently described condition with well-defined clinical and histopathologic features. Eight additional cases from Mexican patients-six cases have been published in the literature, we report 7. In 6 cases, a hyperkeratotic edge was demonstrated histologically.

The role of leptin/adiponectin ratio in metabolic syndrome and diabetes.

The metabolic syndrome comprises a cluster of cardiometabolic risk factors, with insulin resistance and adiposity as its central features. Identifying individuals with metabolic syndrome is important due to its association with an increased risk of coronary heart disease and type 2 diabetes mellitus. Attention has focused on the visceral adipose tissue production of cytokines (adipokines) in metabolic syndrome and type 2 diabetes mellitus, as the levels of the anti-inflammatory adipokine adiponectin are decreased, while proinflammatory cytokines are elevated, creating a proinflammatory state associated with insulin resistance and endothelial dysfunction.