Int J Biol Macromol
March 2024
The surge in global polymeric waste underscores the imperative for biodegradable materials to substitute traditional polymers. Crucially, advancements are needed for emerging technologies like Materials Extrusion (ME) in additive manufacturing, where current biodegradable materials exhibit limitations. This work was based on the development of a biodegradable composite filament.
View Article and Find Full Text PDFSolution blow spinning (SBS) is a promising alternative to produce fibrous matrices for a wide range of applications, such as packaging and biomedical devices. Polycaprolactone (PCL) is a biodegradable polyester commonly used for spinning. The usual choices for producing PCL solutions include chlorinated solvents (CS), such as chloroform.
View Article and Find Full Text PDFL. is a plant available worldwide that has been traditionally used for several medical applications due to its wound healing, anti-inflammatory, and antimicrobial properties. This work aimed to develop and evaluate a nanostructured PCL electrospun dressing with extract encapsulated in nanofibers for applications in wound healing.
View Article and Find Full Text PDFJ Biomed Mater Res B Appl Biomater
February 2023
Type I collagen (Col_1) is one of the main proteins present in the skin extracellular matrix, serving as support for skin regeneration and maturation in its granulation stage. Electrospun materials have been intensively studied as the next generation of skin wound dressing mainly due to their high surface area and fibrous porosity. However, the electrospinning of collagen-based solutions causes degradation of its structure.
View Article and Find Full Text PDFThis study aimed to investigate different types of morphologies obtained using the electrospinning process to produce a material that enables wound healing while performing a controlled release. Using benign solvents, the authors prepared and characterised electrospun polycaprolactone mats loaded with propolis, a popular extract in traditional medicine with potential for skin repair. Different morphologies were obtained from distinct storage periods of the solution before electrospinning to investigate the effect of PCL hydrolysis (average diameters of fibres and beads: 159.
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