Publications by authors named "Javier Jaso"
Article Synopsis
- Dried blood spots (DBSs) allow researchers to study antibodies for diseases like diphtheria, tetanus, and pertussis without needing blood from veins, making sample collection easier.
- In a study with 64 blood samples, the effectiveness of DBSs in tracking these diseases was assessed, showing high sensitivity and specificity for diphtheria and tetanus, while no protection against pertussis was found.
- The correlation between antibody levels in DBSs and plasma was strong for diphtheria and tetanus even after 4 months of storage at low temperatures, but significantly weaker for pertussis, indicating that DBSs are reliable for some markers but not all.
Dried blood spots (DBSs) are an economical and convenient alternative to serum/plasma, which allow for the serological and molecular study of different pathogens. Sixty-four blood samples were collected by venipuncture and spotted onto Whatman™ 903 cards to evaluate the utility of DBSs and the effect of the storage temperature for 120 days after sample collection to carry out serological diagnosis. Mumps, measles and rubella IgG were investigated from DBSs and plasma using an automated chemiluminescent immunoassay.
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