Apple peels as an edible source of phenolic bioactive compounds with antidiabetic and antiglycation properties.

Apples ( Borkh.) are one of the most consumed fruits around the world with a high production of peels as wastes and by-products. In this work, peels from different commercial and local apple samples are explored as a source of phenolic bioactive compounds that could be directly related to the prevention of type 2 diabetes.

Black mulberry ( L) prevents deleterious effects of excess glucose in obese decreasing lipofuscin accumulation and ROS production.

Black mulberries have been traditionally used as antidiabetic agents and are a source of nutrients and phenolic compounds, particularly anthocyanins. The objective of this work is to determine if berries could prevent metabolic and obesity-related disorders using systems and alternative models such as . An aqueous solvent-free extract from fruits rich in phenolic compounds like chlorogenic acid, hyperoside, rutin and cyanidin 3-glucoside was evaluated in the obese model subjected to high glucose concentrations evaluating different parameters such as lipid droplets, lipofuscin accumulation and ROS production.