Publications by authors named "Javier Aracil-Santos"
Introduction/objectives: Asian scores developed to predict unresponsiveness to intravenous immunoglobulin (IVIG) or development of coronary artery aneurysms (CAA) in patients with Kawasaki disease (KD) are not appropriate in Western populations. The purpose of this study is to develop 2 scores, to predict unresponsiveness to IVIG and development of CAA, appropriate for Spanish population.
Method: Data of 625 Spanish children with KD collected retrospectively (2011-2016) were used to identify variables to develop the 2 scores of interest: unresponsiveness to IVIG and development of CAA.
A retrospective study that compared children younger than 6 months versus older children of a Spanish cohort of patients diagnosed with Kawasaki disease between 2011 and 2016 (Kawa-Race study). From the 598 patients recruited, 42 patients were younger than 6 months (7%) and presented more frequently with an incomplete diagnosis of Kawasaki disease (52.4 vs 27.
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- - COVID-19 generally causes less severe illness in children, but during the pandemic, an increase in cases resembling Kawasaki disease (KD) was observed, prompting many hospital admissions to pediatric intensive care units (PICU).
- - A study analyzed KD patients in Spain from January 2018 to May 2020, comparing those who were SARS-CoV-2 positive and negative during the COVID-19 period with cases from the same months in prior years.
- - Key findings revealed that CoV+ patients were older, had different clinical presentations (like incomplete KD), and showed higher inflammation levels compared to PreCoV patients, while also possibly aligning with the criteria for a new condition called pediatric inflammatory multisystem syndrome.
Background: Kawasaki disease (KD) is an acute self-limited systemic vasculitis of unknown etiology affecting mainly children less than 5 years of age. Risk factors for cardiac involvement and resistance to treatment are insufficiently studied in non-Japanese children.
Objective: This study aimed to investigate the epidemiology, clinical features and risk factors for resistance to treatment and coronary artery lesions (CAL) in KD in Spain.