Effect of Helicobacter pylori and Helminth Coinfection on the Immune Response to Mycobacterium tuberculosis.

Tuberculosis remains one of the main causes of morbidity and mortality worldwide despite decades of efforts to eradicate the disease. Although the immune response controls the infection in most infected individuals (90%), the ability of the bacterium to persist throughout the host's life leads to a risk of reactivation. Underlying conditions including human immunodeficiency virus (HIV) infection, organ transplantation, and immunosuppressive therapies are considered risk factors for progression to active disease.

Detection of pathogenic Leptospira in ornamental water fountains from urban sites in Cali, Colombia.

Leptospirosis is a disease endemic to both rural and urban areas of tropical countries and resource-poor communities. Little information is available on the presence of Leptospira spp. in urban water sources.

Effect of treatment failure on the CagA EPIYA motif in strains from Colombian subjects.

Aim: To evaluate effect of treatment failure on and genotypes in () isolates from Colombia.

Methods: One hundred and seventy-six participants infected with from Colombia were treated during 14 d with the triple-standard therapy. Six weeks later, eradication was evaluated by C-Urea breath test.

Genomic variability of isolates of gastric regions from two Colombian populations.

Aim: To compare the genomic variability and the multiple colonization of () in patients with chronic gastritis from two Colombian populations with contrast in the risk of developing gastric cancer (GC): Túquerres-Nariño (High risk) and Tumaco-Nariño (Low risk).

Methods: Four hundred and nine patients from both genders with dyspeptic symptoms were studied. Seventy-two patients were included in whom was isolated from three anatomic regions of the gastric mucosa, (31/206) of the high risk population of GC (Túquerres) and (41/203) of the low risk population of GC (Tumaco).

In vitro effect of amoxicillin and clarithromycin on the 3' region of cagA gene in Helicobacter pylori isolates.

Aim: To evaluate the in vitro effect of amoxicillin and clarithromycin on the cag pathogenicity island (cag PAI).

Methods: One hundred and forty-nine clinical isolates of Helicobacter pylori (H. pylori) cultured from gastric biopsies from 206 Colombian patients with dyspeptic symptoms from a high-risk area for gastric cancer were included as study material.