(R)-Carvone is a potential soil fumigant against Meloidogyne incognita whose likely enzymatic target in the nematode is acetylcholinesterase.

To contribute to the development of new fumigant nematicides for the control of the plant-parasitic nematode Meloidogyne incognita, this study started with 31 volatile organic compounds reported as toxic to nematodes. At 500 μg/mL, α-ionone, (S)-carvone, (R)-carvone, 2-methylpropyl acetate, undecan-2-one, decan-2-one, and dodecan-2-one caused mortalities to M. incognita second-stage juveniles (J2) that were similar to those obtained with the commercial nematicides carbofuran (170 μg/mL) and fluensulfone (42.

Methyl Esters of ()-Cinnamic Acid: Activity against the Plant-Parasitic Nematode and Interaction with Histone Deacetylase.

()-Cinnamaldehyde is very active against but has low persistence in soil. To circumvent this problem, esters of cinnamic acid were evaluated as a substitute for ()-cinnamaldehyde. The best results under assays with second-stage juveniles (J2) were obtained for the methyl esters of ()--fluoro- (), ()--chloro- (), and ()--bromocinnamic acid (), which showed lethal concentrations to 50% (LC) J2 of 168, 95, and 216 μg/mL, respectively.