Publications by authors named "Javier A Barrera-Zarate"

and coinfection has been observed in the diagnostic routine; however, no studies have evaluated their interaction. This study aimed to characterize lesions and possible synergisms in experimentally infected pigs. Four groups of piglets, coinfection (CO), (BRA), (LAW), and negative control (NEG), were used.

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Swine dysentery (SD) is characterized by a severe mucohemorrhagic colitis caused by infection with species. In infected herds the disease causes considerable financial loss due to mortality, slow growth rates, poor feed conversion, and costs of treatment. is the most common etiological agent of SD and infection is usually associated with disease.

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Angiogenesis and cell proliferation in reproductive tissues are essential events for the maintenance of pregnancy, and alterations can lead to compromised fetal development and survival. Porcine reproductive and respiratory syndrome virus 2 (PRRSV-2) induces reproductive disease with negative financial and production impact on the swine industry. PRRSV-2 infection alters placental physiology through inflammatory and apoptotic pathways, yet fetal susceptibility varies.

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To demonstrate the utility of oral fluid (OF) for indirect diagnostic detection of Lawsonia intracellularis (Li), 15 pig farms were studied. Serum and fecal samples were collected from 20 animals from five different age groups on each farm. OF samples were collected from animals in two pens of the same age groups.

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Article Synopsis
  • Lawsonia intracellularis is a challenging bacterium to culture, requiring specialized conditions for isolation, leading to limited available strains and antimicrobial studies.
  • The study successfully isolated two Brazilian and three Thai strains of L. intracellularis and tested various antimicrobials for their effectiveness, with the pleuromutilin group and carbadox showing the highest activity.
  • Results indicated that several commonly used antimicrobials had variable effectiveness against L. intracellularis, and the bacterium showed resistance to lincomycin, gentamicin, and others, highlighting the need for targeted treatment options.
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