Frequency and severity of neutropenia in diffuse large B-cell non Hodgkin's lymphoma after first cycle of chemotherapy comprising cyclophosphamide, doxorubicin, vincristine with prednisolone.

Background: Chemotherapy used for malignant diseases may produce severe neutropenia in first cycle which may compel for dose modification and early termination of therapy. This descriptive cross sectional study was planned to see the frequency and severity of neutropenia after first cycle of chemotherapy comprising cyclophosphamide, doxorubicin, vincristine with prednisolon in patients of diffuse large B-cell non Hodgkin's lymphoma presenting at Oncology Department Combined Military Hospital Rawalpindi from August 2009 to July 2010.

Methods: Thirty patients of diffuse large B-cell non Hodgkin's lymphoma diagnosed on lymph node biopsy presenting for the first time at Oncology Department Combined Military Hospital Rawalpindi were included.

Frequency of bone marrow involvement in Hodgkin's lymphoma on first presentation.

Objective: To determine the frequency of bone marrow involvement in patients of Hodgkin's lymphoma on first presentation at oncology department.

Study Design: Case series.

Place And Duration Of Study: The Oncology Department, Combined Military Hospital, Rawalpindi, from April 2006 to February 2007.