Molecular insight into the structural and functional aspects of arene Ru(II) complexes bearing bulky thiourea ligands.

Herein we report four new arene ruthenium(II) complexes [Ru(η-p-cymene)(L1)кCl] (C1), [Ru(η-benzene)(L1)кCl] (C2) where L1 is N-((2,6-dimethylphenyl)carbamothioyl)benzamide (L1), and [Ru(η-p-cymene)(L2)кCl] (C3), [Ru(η-benzene)(L2)кCl] (C4) where L2 is N-((2,6-diisopropylphenyl)carbamothioyl)benzamide (L2) which were synthesized and evaluated for biological activity. The monodentate coordination of thione sulphur (S) to ruthenium ion along with two terminal chloride was confirmed by X-Ray diffraction analysis thus revealing a typical "piano-stool" pseudo tetrahedral geometry. DPPH radical scavenging activity showed that ligands were less efficient however on complex formation it showed significant efficacy with C4 showing the highest activity.