Publications by authors named "Javaria Sundus"

Article Synopsis
  • * The study investigates how ablating certain central nervous system elements affects motor function and brain damage after an ischemic stroke, along with its impact on NeuroD1 gene therapy.
  • * Results show that CKO mice experienced worse motor dysfunction and increased neuroinflammation after a stroke, indicating that ablation heightens neuron death and reduces the effectiveness of NeuroD1 therapy, pointing to HIF-1α as a potential treatment target.
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Stroke is the most devastating disease, causing paralysis and eventually death. Many clinical and experimental trials have been done in search of a new safe and efficient medicine; nevertheless, scientists have yet to discover successful remedies that are also free of adverse effects. This is owing to the variability in intensity, localization, medication routes, and each patient's immune system reaction.

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