Impact of boron on Glycine max L. to mitigate salt stress by modulating the morpho-physiological and biochemical responses.

Background: Boron (B) is an essential micronutrient in higher plants, contributing to various physiological processes. However, its protective mechanism in mitigating salt stress remained less understood. This study investigates that exogenous boron (0, 1, 2 kg ha) can help alleviate salt stress (0, 60, 120 mM NaCl) in two soybean cultivars AARI-2021 (V1) and Ajmeri (V2).

Advancing conductive cellulosic textiles: Structural, optical and thermoelectric enhancements via innovative metallic oxide deposition.

Traditionally known for their insulating properties, cellulosic textiles have faced limitations in the approval of conducting materials. Specifically, this study investigate the impact of annealing time duration on the structural, morphological, and thermoelectric properties of zinc doped copper oxide (Zn doped CuO) nanostructures deposited onto cellulosic fabric using the Thermal Evaporation Method. Various characterization techniques including x- ray diffraction (XRD), Raman spectroscopy, scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR) and thermoelectric attributes of samples were analyzed.

Long-term adherence to anti-osteoporosis medication and determinants of adherence in the population-based screening trial ROSE.

Unlabelled: Screening initiatives for osteoporosis must facilitate treatment of those at elevated fracture risk. In a randomized controlled trial of 24,229 women, those in the screening group with FRAX ≥ 15% were invited for DXA with AOM treatment offered as per national guidelines. Treatment initiation in the following year was 9.

Managing workplace hazards and environmental contaminants for promoting green human resource management and health and safety in developing economies.

Background: At a global scale, the impact of the manufacturing sector on the environment has led to the increased demand for the sustainable practices and strategies that help the businesses achieve environmental, social, and economic objectives particularly within the context of developing economies.

Objective: This paper addresses this gap by investigating the relationship between employees and firms' environmental performance in the manufacturing sector operating in a developing country, Pakistan-where the environmental focus is sparse and organizational structures rarely follow cross-functional systems.

Methods: Quantitative research was employed and SmartPLS technique was used to test the theoretical model with a valid response rate of 77 percent of senior and middle-level managers of manufacturing firms.

X-Linked Hypophosphatemia Management in Children: An International Working Group Clinical Practice Guideline.

Background: An International Working Group (IWG) developed new guidelines on the diagnosis, evaluation, management, and monitoring of X-linked hypophosphatemia (XLH) in children. Over the past 5 years, important advances have occurred in our understanding of the presentation, complications and treatment of XLH.

Methods: A group of 50 international experts in XLH from Canada, the United States, Europe, Asia and South America, along with methodology experts and patient partners, held 18 teleconference meetings in 2023-2024.

Assessing and Managing Primary Hyperparathyroidism and Fracture Risk in England: A Survey of Medical Professionals.

Purpose: To describe diagnostic approaches and management strategies for patients with primary hyperparathyroidism (PHPT) and recent fracture in England.

Methods: We developed a survey based on a patient at high fracture risk and a new diagnosis of probable PHPT. The survey was circulated among 50 secondary care professionals identified by the Society for Endocrinology Calcium and Bone special interest group.

Silicon-mediated modulation of maize growth, metabolic responses, and antioxidant mechanisms under saline conditions.

Purpose: This study explored how exogenous silicon (Si) affects growth and salt resistance in maize.

Methods: The maize was cultivated in sand-filled pots, incorporating varied silicon and salt stress (NaCl) treatments. Silicon was applied at 0, 2, 4, 6, and 8 mM, and salt stress was induced using 0, 60 and120 mM concentrations.

Management of Isolated Radial Diaphyseal Fractures in the Paediatric Population.

Introduction Paediatric forearm fractures are common, but isolated radial diaphyseal fractures are rare, representing a small subset. Unlike fractures involving both the radius and ulna, these fractures lack well-established management guidelines. The potential for alignment loss during treatment underscores the need for specific protocols.

Sodium-glucose cotransporter 2 inhibitors for chronic kidney disease: Why, when and when not.

Background: Chronic kidney disease (CKD) is a significant healthcare problem. More advanced stages are associated with increased mortality, morbidity and cost. Instigating measures to slow down disease progression at an early stage can save lives, and millions of dollars of taxpayers' money.

Use of carboxymethyl cellulose in polyurethane synthesis for thermal applications.

This research utilizes carboxymethyl cellulose (CMC) as a renewable feedstock in polyurethane synthesis, offering improved thermal stability and potential for biomedical applications. In this study, a series of CMC-based polyurethanes was synthesized by using a step-growth polymerization reaction. The initial step involved the reaction of isophorone diisocyanate (IPDI) with hydroxy-terminated polybutadiene (HTPB) to prepare an isocyanate (-NCO) terminated prepolymer.

Phylogenetic and phylodynamic analysis of respiratory syncytial virus strains circulating in children less than five years of age in Karachi-Pakistan.

Background: Respiratory syncytial virus (RSV) is one of the leading causes of infant morbidity and mortality worldwide, especially in Pakistan. To date, few studies have explored RSV epidemiology in different areas of Pakistan. However, none have performed comprehensive phylogenetic and phylodynamic analyses of RSV strains.

COMPARING STRESS LEVELS AMONG MEDICAL EMERGENCY UNIT WORKERS IN TEACHING HOSPITALS ACROSS LAHORE: A QUANTITATIVE ANALYSIS OF PRECISION.

Background: Stress is characterized as a condition of anxiety or tension spurred on by challenging circumstances. Stress is a normal human reaction that motivates us to deal with obstacles and dangers in our lives. The study aimed to investigate the levels of stress that employees in the medical emergency unit (MEU) industry face and any possible relationship between work satisfaction, and perceived stress.

Relationship Between Serum Interleukin-6 Levels, Systemic Immune-Inflammation Index, and Other Biomarkers Across Different Rheumatoid Arthritis Severity Levels.

Background Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by joint inflammation, pain, and progressive disability. Identifying biomarkers that accurately reflect disease severity is crucial for effective management. Interleukin-6 (IL-6) is a pro-inflammatory cytokine involved in the pathogenesis of RA, and the systemic immune-inflammation index (SII) is emerging as a useful marker of systemic inflammation.

Outcomes of first-line treatment and their association with pretreatment neutrophil-to-lymphocyte ratio in patients with advanced renal cell carcinoma: Insights from a tertiary care institute in Pakistan.

Background: Renal cell carcinomas (RCCs) are renal parenchymal neoplasms that contribute to <5% of cancer cases worldwide. Within the diverse group of renal tumours, clear cell carcinoma is the most common subtype. The recommended first-line treatment for metastatic disease is a tyrosine kinase inhibitor given either as monotherapy or in combination with an immune checkpoint inhibitor, based on improved survival outcomes.

A Literature Review of Cutibacterium Acnes: From Skin Commensal to Pathogen in Shoulder Surgery.

, previously known as , is a gram-positive rod in the pilosebaceous glands and commonly implicated in acne vulgaris. Its role in prosthetic joint infections, particularly in shoulder surgeries, has recently gained attention due to its prevalence around the shoulder girdle. This review collates evidence on the pathogenic role of in shoulder surgeries, discussing preventive measures, risk factors, clinical presentation, investigation, and treatment strategies.

Synthesis and optimization of molecular weight of chitosan and carboxymethyl cellulose based polyurethanes.

For the first time in this research, using a mixture design approach, polyurethanes (PUs) based on chitosan (CSN) and carboxymethyl cellulose (CMC) were synthesized to develop a high molecular weight polymer. In the synthesis process, a reaction between isophorone diisocyanate (IPDI) and hydroxyl-terminated polybutadiene was carried out to synthesize a prepolymer containing free NCO groups at the corners. This prepolymer was further reacted with changing moles ratio of CSN and CMC following the principles of statistical mixture design.

Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.

Background: Findings from the Maternal Vitamin D Osteoporosis Study (MAVIDOS) trial demonstrated a positive effect of gestational cholecalciferol supplementation on offspring bone mineral density (BMD) at age 4 y. Demonstrating the persistence of this effect is important to understanding whether maternal vitamin D supplementation could be a useful public health strategy to improving bone health.

Objectives: We investigated whether gestational vitamin D supplementation increases offspring BMD at ages 6-7 y in an exploratory post-hoc analysis of an existing trial.

The Fracture Phenotypes in Women and Men of 50 Years and Older with a Recent Clinical Fracture.

Purpose Of Review: We review the literature about patients 50 years and older with a recent clinical fracture for the presence of skeletal and extra-skeletal risks, their perspectives of imminent subsequent fracture, falls, mortality, and other risks, and on the role of the fracture liaison service (FLS) for timely secondary fracture prevention.

Recent Findings: Patients with a recent clinical fracture present with heterogeneous patterns of bone-, fall-, and comorbidity-related risks. Short-term perspectives include bone loss, increased risk of fractures, falls, and mortality, and a decrease in physical performance and quality of life.