Publications by authors named "Javahir Hajibabazade"
Clin Exp Metastasis
October 2024
Article Synopsis
- Chemotherapy effectively kills rapidly dividing cancer cells but struggles to eliminate slower-dividing cancer stem cells and dormant cells, leading to reduced effectiveness with prolonged treatment.
- A study was conducted using a specific cancer cell model to analyze how chemotherapy affects gene expression related to cancer cell survival and dormancy by comparing treated and untreated cells in mice.
- Findings revealed that chemotherapy alters the expression of genes associated with cancer cell dormancy and survival, while downregulating pathways that initiate cell death, suggesting new targets for improving treatment outcomes against drug resistance.
Article Synopsis
- The study investigates the link between the C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of colorectal polyps in the Azerbaijani population, aiming to enhance personalized medicine for CRC prevention.
- It compared 125 patients with colon polyps to 155 healthy controls, analyzing DNA through specific laboratory techniques.
- Results showed no significant associations between the gene variants and disease risk, indicating that factors like age, sex, smoking, and alcohol use did not differ significantly between the patient and control groups.
