Surgical outcome of trans-sphenoidal approach to pituitary adenoma in adult patients: 10 years experience in northwest of Iran.

Pituitary adenoma (PA) is a frequent intracranial lesion, that needs surgical evacuation. In this study, we evaluated the surgical outcome of PA treated via endoscopic and microscopic trans-sphenoidal approach. In this retrospective cross-sectional study, we evaluate ten years of PA surgery experience in the northwest of Iran.

Evaluation of the risk factors associated with emergency department boarding: A retrospective cross-sectional study.

Purpose: Boarding is a common problem in the emergency department (ED) and is associated with poor health care and outcome. Imam Khomeini Hospital is the main healthcare center in Urmia, a metropolis in the northwest of Iran. Due to the overcrowding and high patient load, we aim to characterize the rate, cause and consequence of boarding in the ED of this center.

Infection in Disc Material and Different Antibiotic Susceptibility in Patients With Lumbar Disc Herniation.

Background: Low back pain is an important, worldwide clinical problem from which human populations are suffering. It has been suggested that is associated with low back pain. The objective of this clinical study is to evaluate the infection in the disc material and antibiotic susceptibility in patients with disc herniation.

What do You Expect from Patients with Severe Head Trauma?

Background: Head trauma is one of the most common mortality and morbidity causes in adolescent. Numerous studies have been conducted on changes in laboratory results and mortality and morbidity prognostic factors; however, the obtained results have been varied and controversial. The aim of this study is to evaluate changes in laboratory findings and arterial blood gas (ABG) analyses test at admission and investigation of the relation between these changes with outcomes in patients with traumatic brain injury.

Riluzole Can Improve Sensory and Motor Function in Patients with Acute Spinal Cord Injury.

Background: Spinal cord injury (SCI) causes sensory, motor function and consists of a large proportion of patients that referred to trauma centers. Riluzole blocks the sodium channels and has possible supportive effects on the central nervous system. The aim of this study was to investigate the effect of riluzole on sensory and motor improvement and pain level in patients with acute SCI.

Minimal Dose of Tranexamic Acid Is Effective in Reducing Blood Loss in Complex Spine Surgeries: A Randomized Double-Blind Placebo Controlled Study.

Study Design: A randomized double-blind placebo controlled study.

Purpose: In the present study, we aimed to assess the efficacy of tranexamic acid (TXA) in reducing blood loss after laminectomy and posterolateral fusion of the spine.

Overview Of Literature: Blood loss is the most significant complication involved with surgery, especially in spinal surgery.

Meningioma in Fourth Ventricle of Brain: A Case Report and Literature Review.

Meningiomas are benign tumors origin from central nervous system. They usually involve cephalic, paravertebral soft tissues, skin and in rare cases in the ear, temporal bone, mandible, foot, lung, and mediastinum. In this case, we report an unusual case of meningioma which placed in the fourth ventricle.

Effects of Atorvastatin in Patients with Acute Spinal Cord Injury.

Study Design: Clinical trial study.

Purpose: The aim of this study was to evaluate the effect of atorvastatin on sensory and motor function in patients with acute spinal cord injury.

Overview Of Literature: The prevalence and incidence of traumatic spinal cord injury are increasing.

Cause-specific mortality among women of reproductive age: Results from a population-based study in an Iranian community.

Purpose Of Study: This study was conducted to evaluate the levels, patterns, and causes of mortality among women of reproductive age in Northwestern Iran.

Methods: Deaths were determined for females resident in West Azerbaijan Province of Iran and who died between March 2013 to February 2014 using reproductive age mortality survey (RAMOS). Causes of death were ascertained by verbal autopsy (VA) and classified based on the International Classification of Diseases, tenth revision (ICD-10).

The roles of Wnt/β-catenin pathway in tissue development and regenerative medicine.

Regenerative medicine is a translational field which combines tissue engineering and molecular biology to construct spare organs or help injured or defective tissues to regenerate or restore their normal functions. This is particularly important with specific organs such as heart, central nervous system, retina, or limbs which possess very limited regenerative capacity. As such, regenerative medicine has received peculiar attention in the last decade.

The distribution of infection with Propionibacterium acnes is equal in patients with cervical and lumbar disc herniation.

Background: Cervical and back pains are important clinical problems affecting human populations globally. It is suggested that Propionibacterium acnes (P. acnes) is associated with disc herniation.

Modic changes in the adjacent vertebrae due to disc material infection with Propionibacterium acnes in patients with lumbar disc herniation.

Introduction: Modic changes (MCs) in vertebral bones are induced by two mechanisms of mechanical factors and infection. As Propionibacterium acnes (P. acnes) have been reported to be associated with LBP.

Can Serum Glucose Level in Early Admission Predict Outcome in Patients with Severe Head Trauma?

Background: Traumatic brain injury is a major general health concern. This study aims to evaluate a possible relationship between the serum level of glucose during admission and the outcome of patients with severe traumatic brain injury.

Methods: In this prospective study, 80 patients with severe traumatic brain injury were recruited from the emergency department of Urmia Imam Khomeini Hospital.

Anti-fatigue mats, low back pain, and electromyography: An interventional study.

Objectives: Increasing bilateral gluteus medius co-activation has been identified as one of the most important factors in developing low back pain due to prolonged standing in healthy people. This study aims to investigate the impact of an anti-fatigue mat on the bilateral gluteus medius co-activation pattern and to report the low back pain subjectively in 2 different standing positions on the normal rigid surface and on the anti-fatigue mat.

Material And Methods: While carrying out an easy simulated profession, 16 participants who had no low back pain background were requested to stand for 2 h in each position, with and without using the anti-fatigue floor mat, respectively.

Immunotherapy of prolactinoma with a T helper 1 activator adjuvant and autoantigens: a case report.

Objective: To date, efforts to reliably manipulate the immune system to promote tumor regression in the brain have been disappointing. We report a unique experience of successful immunotherapy to treat a pituitary macroprolactinoma.

Methods: A 31-year-old woman with an established history of pituitary macroprolactinoma who had undergone tumor resection followed by radiation was admitted to our clinic.