Temperature dependent magnetorelaxometry of magnetic nanoparticle ensembles.

Magnetorelaxometry imaging (MRXI) is a non-invasive, quantitative imaging technique for magnetic nanoparticles (MNPs). The image resolution of this technique significantly depends on the relaxation amplitude (Δ). For this work, we measured the room temperature (299 K) relaxation signals of eight commercial MNP sample systems with different magnetic properties, in both fluid and immobilized states, in order to select the most suitable sample for a particular MRXI setting.

Human-sized quantitative imaging of magnetic nanoparticles with nonlinear magnetorelaxometry.

Magnetorelaxomety imaging (MRXI) is a noninvasive imaging technique for quantitative detection of magnetic nanoparticles (MNPs). The qualitative and quantitative knowledge of the MNP distribution inside the body is a prerequisite for a number of arising biomedical applications, such as magnetic drug targeting and magnetic hyperthermia therapy. It was shown throughout numerous studies that MRXI is able to successfully localize and quantify MNP ensembles in volumes up to the size of a human head.

Developing magnetorelaxometry imaging for human applications.

Magnetic nanoparticles (MNPs) are a promising tool in biomedical applications such as cancer therapy and diagnosis, where localization and quantification of MNP distributions are often mandatory. This can be obtained by magnetorelaxometry imaging (MRXI).In this work, the capability of MRXI for quantitative imaging of MNP inside larger volumes such as a human head is investigated.

Evaluating selection criteria for optimized excitation coils in magnetorelaxometry imaging.

Magnetorelaxometry imaging (MRXI) is an experimental imaging technique applicable for noninvasive, qualitative and quantitative imaging of magnetic nanoparticles (MNPs). Accurate reconstructions of nanoparticle distributions are crucial for several novel treatment methods employing MNPs such as magnetic drug targeting or magnetic hyperthermia therapy. Hence, it is desirable to design MRXI setups such that the reconstruction accuracy is maximized for a given set of design parameters.

Pulsed Optically Pumped Magnetometers: Addressing Dead Time and Bandwidth for the Unshielded Magnetorelaxometry of Magnetic Nanoparticles.

Magnetic nanoparticles (MNP) offer a large variety of promising applications in medicine thanks to their exciting physical properties, e.g., magnetic hyperthermia and magnetic drug targeting.

Quantitative 2D Magnetorelaxometry Imaging of Magnetic Nanoparticles using Optically Pumped Magnetometers.

For biomagnetical applications exploiting physical properties of magnetic nanoparticles (MNP), e.g., magnetic hyperthermia, knowledge about the quantitative spatial MNP distribution is crucial, which can be extracted by magnetorelaxometry (MRX) imaging.