The effect of acute changes in glomerular filtration rate on common biochemical tests.

Objectives: To characterise the effect of acute kidney injury on the concentration of common biochemical analytes.

Design: and methods: Pairs of serum or plasma samples from the same patients routinely submitted to the laboratory were subject to further analysis based on changes in serum creatinine within 72 h. Samples collected from patients on dialysis were excluded.

Effect of renal function on serum cardiac troponin T--Population and individual effects.

Background: Elevations of serum cardiac troponin T (cTnT) have been described in patients with end stage chronic kidney disease (CKD) although the mechanism is unknown, whether from increased production or decreased clearance. Less is known about cTnT in short term changes in renal function and in lesser degrees of renal impairment.

Objectives: This study aimed to investigate the effect of renal function changes on cTnT within individuals and characterise the distribution of cTnT according to renal function in the population.