Extravascular closure for patients with high-risk femoral anatomy.

Background: Vascular closure devices (VCDs) improve patient comfort and decrease time to ambulation. However, VCD studies have excluded patients with high-risk femoral artery anatomy; we examined the safety and efficacy of clip-based extravascular closure in this high-risk group.

Methods: We performed a prospective registry enrolling 98 consecutive patients undergoing diagnostic coronary angiography.