Publications by authors named "Jason Stankiewicz"

Article Synopsis
  • SARS-CoV-2 not only infects the respiratory system but also causes gastrointestinal (GI) symptoms, leading researchers to study its GI effects in both rhesus macaques and humans.
  • In macaques, infection resulted in viral RNA found in both the respiratory tract and stool, along with decreased levels of certain immune cells in the intestine, suggesting immune disturbance.
  • The study highlighted the translocation of bacteria across the gut barrier during infection and noted that humans recovering from COVID-19 showed decreases in inflammatory markers, indicating a resolution of inflammation linked to GI issues.
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Background: Recent advances in device technology and image analysis software used to assess the sublingual microcirculation have expanded clinicians' understanding of hemodynamics beyond assessments of blood pressure and end-organ function to provide unique insight into blood flow at the tissue level. Similarly, significant advances in virtual education and telemedicine have transpired recently, especially during the coronavirus disease (COVID-19) pandemic. However, the training of clinicians to acquire microcirculation images continues to rely on in-person instruction, which can be limited by available local expertise and resources, as well as geographic access to instructors.

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Handheld vital microscopy (HVM) can deepen our understanding of hematologic diseases and therapeutics. However, limited reports have assessed human microcirculation during profound anemia, and response to hemoglobin-based oxygen carriers (HBOCs). A 58-year-old woman presented with constitutional symptoms and was diagnosed with acute myeloblastic leukemia.

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