Publications by authors named "Jason Partridge"
Article Synopsis
- Laminar flow in the arterial tree protects endothelial cells (EC) from inflammation and atherosclerosis by influencing the way NF-kappaB transcription factors operate.
- Experiments showed that shear stress enhances expression of protective molecules and decreases proinflammatory ones in human umbilical vein endothelial cells (HUVEC) when exposed to TNFalpha.
- The study confirms that shear stress enhances EC's ability to respond protectively through NF-kappaB activation, suggesting that this modulation may play a key role in preventing atherosclerosis.
