Publications by authors named "Jason Miclat"
Channels (Austin)
July 2016
Article Synopsis
- The research confirms that KCa3.1 (IKCa) channels are present in CA1 hippocampal pyramidal cells and play a role in regulating neuron behavior through a slow afterhyperpolarization.
- The study employs single cell RT-PCR to identify mRNA sequences related to the IKCa channel, highlighting key binding sites for four specific blockers.
- It also discusses challenges in effectively applying the IKCa blocker TRAM-34 internally, noting that starting the drug treatment at the beginning of experiments is not feasible due to rapid drug action after being introduced for whole-cell recordings.
