Assessment of Aggressiveness of Breast Cancer Using Simultaneous 18F-FDG-PET and DCE-MRI: Preliminary Observation.

Purpose: This study aims to investigate the feasibility of using simultaneous breast MRI and PET to assess the synergy of MR pharmacokinetic and fluorine-18 fluorodeoxyglucose (F-FDG) uptake data to characterize tumor aggressiveness in terms of metastatic burden and Ki67 status.

Methods: Twelve consecutive patients underwent breast and whole-body PET/MRI. During the MR scan, PET events were simultaneously accumulated.

Assessment of Background Parenchymal Enhancement and Lesion Kinetics in Breast MRI of BRCA 1/2 Mutation Carriers Compared to Matched Controls Using Quantitative Kinetic Analysis.

Rationale And Objectives: To investigate whether quantitative kinetic analysis of lesions and background parenchyma in breast magnetic resonance imaging can elucidate differences between BRCA carriers and sporadic controls with high risk for breast cancer.

Materials And Methods: Fifty-nine BRCA and 59 control cases (49 benign, 10 malignant) were examined in this study. Principal component analysis was applied for quantitative analysis of dynamic signal in background parenchyma (B) and lesion (L) in terms of initial enhancement ratio (IER) and delayed enhancement ratio (DER).

Use of computed tomography to assess volume change after endoscopic orbital decompression for Graves' ophthalmopathy.

Background: Orbital decompression is frequently performed in the management of patients with sight-threatening and disfiguring Graves' ophthalmopathy. The quantitative measurements of the change in orbital volume after orbital decompression procedures are not definitively known. Furthermore, the quantitative effect of septal deviation on volume change has not been previously analyzed.

Evaluation of the kinetic properties of background parenchymal enhancement throughout the phases of the menstrual cycle.

Purpose: To develop and apply a semiautomatic method of segmenting fibroglandular tissue to quantify magnetic resonance (MR) imaging contrast material-enhancement kinetics of breast background parenchyma (BP) and lesions throughout the phases of the menstrual cycle in women with benign and malignant lesions.

Materials And Methods: The institutional review board approved this retrospective HIPAA-compliant study, and informed consent was waived. From December 2008 to August 2011, 58 premenopausal women who had undergone contrast material-enhanced MR imaging and MR imaging-guided biopsy were identified.

Computed tomography imaging of acute neck inflammatory processes.

Early diagnosis and management of neck infections and inflammatory processes is a common challenge for emergency and ear, neck and throat physicians, as well as radiologists. Emergency neck infections are diverse in their presentation, ranging from a transient enlargement of a lymph node to a rapidly spreading necrotizing fasciitis. Symptoms and signs, with the clinical history, usually suggest the diagnosis.

Emergency head & neck imaging: infections and inflammatory processes.

Neck infections are fairly common in the emergency setting, affecting a broad spectrum of the patient population. Care should be taken not only to distinguish these conditions from other noninfectious origin such as malignancy but also to guide acute clinical management. A familiarity with neck anatomy, the imaging modalities used for investigation of such conditions, as well as common findings on imaging are critical to the care of affected patients.