Pentoxifylline or theophylline use in hospitalized COVID-19 patients requiring oxygen support.

Introduction: The phosphodiesterase inhibitors theophylline and pentoxifylline have anti-inflammatory properties that may make them useful in COVID-19 pneumonia. We conducted a retrospective review of hospitalized COVID-19 patients requiring oxygen who received these drugs.

Objectives: To examine the potential efficacy and safety of theophylline and pentoxifylline in COVID-19 pneumonia patients.