Serotonin enhances urinary bladder nociceptive processing via a 5-HT3 receptor mechanism.

Serotonin from the descending pain modulatory pathway is critical to nociceptive processing. Its effects on pain modulation may either be inhibitory or facilitatory, depending on the type of pain and which receptors are involved. Little is known about the role of serotonergic systems in bladder nociceptive processing.

Mechanized metrics: from verse science to laboratory prosody, 1880-1918.

From roughly the 1880s on, a methodical verse "science" was beginning to assert itself. Gripped by the thought of articulating an objective, fact-based metrics, poetry scientists brought to bear on the traditional verse-line principles of observation and, later, on full-blown experimental practices—not to mention a curious array of instrumentation. By the turn of the century, metrical verse was being subjected to a rigorous measurement regime, which employed techniques and apparatuses derived from the new disciplines of experimental physiology and psychology.