The relationship of dose to nerve volume in predicting pain recurrence after stereotactic radiosurgery in trigeminal neuralgia.

OBJECTIVE Approximately 75%-92% of patients with trigeminal neuralgia (TN) achieve pain relief after Gamma Knife surgery (GKS), although a proportion of these patients will experience recurrence of their pain. To evaluate the reasons for durability or recurrence, this study determined the impact of trigeminal nerve length and volume, the nerve dose-volume relationship, and the presence of neurovascular compression (NVC) on pain outcomes after GKS for TN. METHODS Fifty-eight patients with 60 symptomatic nerves underwent GKS for TN between 2013 and 2015, including 15 symptomatic nerves secondary to multiple sclerosis (MS).

Clinical correlation of previously undetected cancer-related incidental findings on CT planning scans for radiation therapy.

Objective: The purpose of our study was to determine the management and cancer outcome of incidental cancer-related findings reported on CT radiation treatment planning scans.

Materials And Methods: We conducted a retrospective review of CT planning scans performed from 2004 to 2006 with diagnostic radiology reports. We previously found 45 (8%) cancer-related findings, defined as any previously unknown radiologic finding that could potentially change the staging or treatment of the cancer, in the 580 CT scans reviewed.

Implications of previously undetected incidental findings on 3D CT simulation scans for radiation therapy.

Purpose: To determine the frequency of significant incidental findings on diagnostic quality simulation computed tomographic (CT) scans for radiotherapy planning.

Methods And Materials: An institutional review board--approved retrospective review of radiation simulation CT scans with diagnostic radiology reports, performed between 2004 and 2006, was conducted to identify incidental findings, defined as previously unreported findings. An incidental finding was classified as a cancer-related finding (CRF) if it could potentially change the staging and treatment of the cancer.