Substance misuse over the first 18 months of specialized intervention for first episode psychosis.

Aim: Examine substance misuse over the first 18 months of first-episode psychosis treatment.

Method: Clinicians rated alcohol and drug (mostly cannabis) misuse for 243 individuals followed prospectively. Assessments were completed at baseline and after 3, 6 and 18 months.

Sociodemographic and clinical characteristics of patients presenting with first-episode psychosis and concurrent substance misuse.

Aims: To determine the incidence of concurrent substance misuse among individuals entering first-episode psychosis treatment, and examine whether patients with concurrent substance misuse differ on variables relevant to service planning.

Methods: Consecutive patients (n=376) were assessed using standardized instruments.

Results: Twenty-two per cent met abuse or dependence criteria for a single substance, and 8% met criteria for two substances.

A waitlist control-group study of cognitive, mood, and quality of life outcome after posteroventral pallidotomy in Parkinson disease.

Object: The aim of this study was to examine neuropsychological outcome from unilateral posteroventral pallidotomy (PVP) in Parkinson disease while controlling for confounding factors such as test practice and disease progression.

Methods: Participants underwent baseline and 2-month follow-up assessments of cognition, quality of life, mood, and motor functioning. The surgery group (22 patients) underwent PVP (15 left, seven right) after baseline assessment.